Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | PRF1 | P14222 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7059004 | 0.92 | MMP13 (0.35) | ALDH1A1KMT2APRF1MEN1MMP13 | |
| SCHEMBL7053127 | 0.90 | MMP13 (0.33) | ALDH1A1KMT2AMEN1MMP13 | |
| SCHEMBL7055796 | 0.89 | KMT2A (0.31) | ALDH1A1KMT2AMEN1MMP13 | |
| SCHEMBL7052572 | 0.89 | SMN1; SMN2 (0.35) | ALDH1A1KMT2AMEN1MMP13 | |
| SCHEMBL7057127 | 0.89 | KMT2A (0.35) | ALDH1A1KMT2AMEN1MMP13 | |
| SCHEMBL7057502 | 0.89 | ALDH1A1 (0.38) | ALDH1A1KMT2AMMP13 | |
| SCHEMBL7352584 | 0.88 | MMP13 (0.42) | MMP13 | |
| SCHEMBL7059375 | 0.88 | LMNA (0.40) | KMT2AMMP13 | |
| SCHEMBL7060171 | 0.87 | MCHR1 (0.36) | ALDH1A1KMT2AMMP13 | |
| SCHEMBL7054787 | 0.84 | HSD17B2 (0.34) | ALDH1A1KMT2AMEN1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6333324-B1 | FOR THERAPY AND PROPHYLAXIS OF MATRIX METALLOPROTEINASES (MMP) OR TUMOR NECROSIS FACTOR .ALPHA. (TNF.ALPHA.), MEDIATED DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-12-25 | — | — | US | disclosed |