SCHEMBL796299

SCHEMBL796299

Cc1ccc(-c2cc(C)cc(=O)n2O)cc1

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GLO1 Q04760 5/20 0.53
ADORA2B P29275 2/20 0.51
MAOA P21397 2/20 0.49
MAOB P27338 2/20 0.49
IDH1 O75874 8/20 0.46
ADORA2A P29274 1/20 0.46
NR1I2 O75469 1/20 0.41
KDM4B O94953 1/20 0.41
CHRM1 P11229 1/20 0.41
TBXA2R P21731 1/20 0.41
ADRA1A P35348 1/20 0.41
DOHH Q9BU89 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11847794 0.87 GLO1 (0.49) GLO1ADORA2BMAOAMAOBIDH1
SCHEMBL11851322 0.87 GLO1 (0.68) GLO1ADORA2BMAOAMAOBIDH1
SCHEMBL11855309 0.84 IDH1 (0.62) GLO1ADORA2BMAOAMAOBIDH1
SCHEMBL10730315 0.84 GLO1 (0.48) GLO1ADORA2BMAOAMAOBIDH1
SCHEMBL27927216 0.83 IDH1 (0.50) GLO1IDH1
SCHEMBL11853685 0.82 ACHE (0.46) GLO1MAOAMAOBIDH1
SCHEMBL10724036 0.80 GLO1 (0.50) GLO1IDH1
SCHEMBL10726843 0.80 GLO1 (0.49) GLO1IDH1
SCHEMBL10726798 0.80 GLO1 (0.41) GLO1ADORA2BIDH1NR1I2KDM4B
SCHEMBL10726768 0.78 IDH1 (0.41) GLO1IDH1NR1I2KDM4BCHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4552754-A Hair cosmetic composition LION CORPORATION (JP) 1985-11-12 US claimed
US-4185106-A Pyridones as antidandruff agents HOECHST AKTIENGESELLSCHAFT (DE) 1980-01-22 US claimed
EP-4413055-B1 STABILIZED RHEOLOGY MODIFIER EMULSIONS LUBRIZOL ADVANCED MAT INC (US) 2025-12-03 EP disclosed
US-20250002704-A1 STABILIZED RHEOLOGY MODIFIER EMULSIONS LUBRIZOL ADVANCED MATERIALS, INC. (US) 2025-01-02 US disclosed
EP-4413055-A1 STABILIZED RHEOLOGY MODIFIER EMULSIONS Lubrizol Advanced Materials, Inc. (US) 2024-08-14 EP disclosed
CN-118076656-A Stabilized rheology modifier emulsions 路博润先进材料公司 2024-05-24 CN disclosed
EP-3091958-B1 COSMETIC COMPOSITION COMPRISING CATIONIC SURFACTANT(S), ANTIDANDRUFF AGENT(S), LIQUID NON-SILICEOUS FATTY SUBSTANCE(S), AND NON-POLYMERIC THICKENING AGENT(S) OREAL (FR) 2024-04-03 EP disclosed
EP-3389613-B1 COSMETIC COMPOSITION COMPRISING AN ANIONIC SURFACTANT, AT LEAST 3.5% BY WEIGHT OF A FATTY ACID AND AN ANTIDANDRUFF AGENT OREAL (FR) 2023-10-11 EP disclosed
EP-4241758-A2 ANTI-DANDRUFF COMPOSITION L'OREAL (FR) 2023-09-13 EP disclosed
WO-2023059784-A1 STABILIZED RHEOLOGY MODIFIER EMULSIONS LUBRIZOL ADVANCED MATERIALS, INC. (US) 2023-04-13 WO disclosed
CN-108430443-B Cosmetic composition comprising anionic surfactant, at least 3.5% by weight of fatty acid and antidandruff agent 欧莱雅 2023-01-03 CN disclosed
EP-1064916-A1 Cosmetic compositions containing an amphoteric polymer and an anti-dandruff agent and their uses L'OREAL (FR) 2001-01-03 EP disclosed
EP-1051203-A1 ANTIMICROBIAL HYDROGEL FORMING ABSORBENT POLYMERS THE PROCTER & GAMBLE COMPANY (US) 2000-11-15 EP disclosed
WO-1999038541-A1 ANTIMICROBIAL HYDROGEL FORMING ABSORBENT POLYMERS THE PROCTER & GAMBLE COMPANY (US) 1999-08-05 WO disclosed
EP-0422508-B2 Liquid detergent composition KAO CORP (JP) 1998-03-18 EP disclosed
EP-0422508-A2 Liquid detergent composition KAO CORPORATION (JP) 1991-04-17 EP disclosed
US-4711775-A ANTIDANDRUFF HAIR LOTIONS AND SHAMPOOS HOECHST AKTIENGESELLSCHAFT (DE) 1987-12-08 US disclosed
US-4552754-A Hair cosmetic composition LION CORPORATION (JP) 1985-11-12 US disclosed
US-4185106-A Pyridones as antidandruff agents HOECHST AKTIENGESELLSCHAFT (DE) 1980-01-22 US disclosed
US-3972888-A Process for the preparation of 1-hydroxy-pyridones HOECHST AKTIENGESELLSCHAFT (DT) 1976-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250002704-A1 STABILIZED RHEOLOGY MODIFIER EMULSIONS SORD, SCD, DEGS1 GLO1 1671/4885ADORA2B 2411/4885MAOA 4139/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.