Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTR1E | P28566 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL260488 | 0.75 | MAPT (0.49) | MAPTMEN1KMT2AMAPK1GAA | |
| SCHEMBL4321214 | 0.74 | MAPT (0.57) | MAPTMEN1KMT2AMAPK1GAA | |
| SCHEMBL7979367 | 0.71 | PDE3B (0.51) | MAPTMEN1KMT2AMAPK1GAA | |
| SCHEMBL11846284 | 0.66 | MBD2 (0.41) | MAPTMEN1KMT2AGAAPKM | |
| SCHEMBL4321210 | 0.65 | GAA (0.49) | MAPTMEN1KMT2AMAPK1GAA | |
| SCHEMBL3450422 | 0.64 | CYP19A1 (0.47) | MAPTLMNAPKMALDH1A1NOTUM | |
| SCHEMBL31714699 | 0.64 | CASP1 (0.49) | MAPTMEN1KMT2AGAAL3MBTL1 | |
| SCHEMBL3832637 | 0.64 | CASP6 (0.52) | MEN1KMT2AGAAL3MBTL1LMNA | |
| SCHEMBL9668896 | 0.64 | APOBEC3G (0.56) | MAPTMEN1KMT2ANPSR1LMNA | |
| SCHEMBL28198 | 0.63 | CA1 (0.67) | MAPTMAPK1GAALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001000601-A1 | NOVEL 4-(2-OXODIHYDROOXADIAZINYLPHENYL)AMIDES AND THE USE THEREOF FOR TREATING ANEMIA | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-04 | — | — | WO | disclosed |