Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.38 |
| ▸ | CA1 | P00915 | 6/20 | 0.38 |
| ▸ | CA2 | P00918 | 6/20 | 0.38 |
| ▸ | CA7 | P43166 | 6/20 | 0.38 |
| ▸ | CA9 | Q16790 | 6/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.38 |
| ▸ | NNMT | P40261 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997381 | 0.89 | KMT2A (0.42) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10530389 | 0.74 | ALDH1A1 (0.35) | CA12CA1CA2CA7CA9 | |
| SCHEMBL19664383 | 0.73 | ACACB (0.36) | CA12CA1CA2CA7CA9 | |
| SCHEMBL22882734 | 0.72 | ALDH1A1 (0.50) | CA12CA1CA2CA7CA9 | |
| Benzene SCHEMBL8717860 | 0.71 | TSHR (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1792881 | 0.71 | TSHR (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7973627 | 0.71 | ALDH1A1 (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7983380 | 0.71 | KMT2A (0.45) | NNMTTSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL20398675 | 0.69 | TSHR (0.43) | CA12CA1CA2CA7CA9 | |
| SCHEMBL12220708 | 0.69 | SMN1; SMN2 (0.56) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007415-A1 | METHOD OF PRODUCING PYRIDAZINE-3,6-DICARBOXYLIC ACID ESTERS | LONZA AG (CH) | 2001-02-01 | — | — | WO | disclosed |
| WO-2001007416-A1 | METHOD OF PRODUCING PYRIDAZINE CARBOXYLIC ACID DERIVATIVES | LONZA AG (CH) | 2001-02-01 | — | — | WO | disclosed |