Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963225 | 0.89 | CA12 (0.38) | KMT2AMEN1CA12CA1CA2 | |
| SCHEMBL7983380 | 0.84 | KMT2A (0.45) | KMT2ALMNAHPGDMEN1SMN1; SMN2 | |
| SCHEMBL7994150 | 0.77 | KMT2A (0.42) | KMT2ALMNAHPGDMEN1SMN1; SMN2 | |
| SCHEMBL4039966 | 0.74 | LMNA (0.41) | KMT2ALMNAMEN1HTTSMN1; SMN2 | |
| SCHEMBL6968314 | 0.74 | LMNA (0.45) | KMT2ALMNAMEN1HTTSMN1; SMN2 | |
| SCHEMBL15881082 | 0.73 | ALDH1A1 (0.41) | KMT2ALMNAMEN1HTTSMN1; SMN2 | |
| SCHEMBL1295778 | 0.72 | ALDH1A1 (0.39) | KMT2ALMNACHRNB2CHRNA4 | |
| SCHEMBL21991449 | 0.68 | KMT2A (0.50) | KMT2ALMNAHPGDMEN1HTT | |
| SCHEMBL29862129 | 0.67 | — | — | |
| SCHEMBL321951 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007416-A1 | METHOD OF PRODUCING PYRIDAZINE CARBOXYLIC ACID DERIVATIVES | LONZA AG (CH) | 2001-02-01 | — | — | WO | disclosed |