Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 1/20 | 0.63 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | LTA4H | P09960 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | TACR3 | P29371 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2789468 | 0.89 | TEAD1 (0.66) | TEAD1TEAD3NPC1RAB9AALDH1A1 | |
| SCHEMBL7963235 | 0.86 | TEAD1 (0.63) | TEAD1TEAD3NPC1RAB9AALDH1A1 | |
| SCHEMBL3830625 | 0.83 | TEAD1 (0.73) | TEAD1TEAD3NPC1RAB9AALDH1A1 | |
| SCHEMBL8235668 | 0.81 | TEAD1 (0.70) | TEAD1TEAD3NPC1RAB9AALDH1A1 | |
| SCHEMBL7973736 | 0.80 | GRIN2D (0.53) | TEAD1TEAD3LTA4HMEN1KMT2A | |
| SCHEMBL13913916 | 0.78 | TEAD1 (0.67) | TEAD1TEAD3NPC1RAB9AALDH1A1 | |
| SCHEMBL2158159 | 0.76 | GPR119 (0.65) | TEAD1TEAD3CHEK2 | |
| SCHEMBL21763292 | 0.76 | TACR3 (0.71) | ALDH1A1LMNAMEN1KMT2ATACR3 | |
| SCHEMBL1277166 | 0.75 | FAAH (0.52) | TEAD1TEAD3ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7031618 | 0.75 | TEAD1 (0.58) | TEAD1TEAD3TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |