Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 1/20 | 0.70 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.70 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3830625 | 0.88 | TEAD1 (0.73) | TEAD1TEAD3NPC1RAB9AALDH1A1 | |
| SCHEMBL2158159 | 0.84 | GPR119 (0.65) | TEAD1TEAD3CHEK2 | |
| SCHEMBL13913916 | 0.83 | TEAD1 (0.67) | TEAD1TEAD3NPC1RAB9AALDH1A1 | |
| SCHEMBL2789468 | 0.83 | TEAD1 (0.66) | TEAD1TEAD3NPC1RAB9AALDH1A1 | |
| SCHEMBL7963237 | 0.81 | TEAD1 (0.63) | TEAD1TEAD3CHEK2NPC1RAB9A | |
| SCHEMBL7963235 | 0.81 | TEAD1 (0.63) | TEAD1TEAD3NPC1RAB9AALDH1A1 | |
| SCHEMBL3356937 | 0.79 | TEAD1 (0.60) | TEAD1TEAD3NPC1RAB9AALDH1A1 | |
| SCHEMBL25120223 | 0.78 | FAAH (0.51) | TEAD1TEAD3ALDH1A1LMNATSHR | |
| SCHEMBL1332206 | 0.78 | TEAD1 (0.60) | TEAD1TEAD3NPC1RAB9AALDH1A1 | |
| SCHEMBL16332966 | 0.78 | CARM1 (0.54) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007089462-A2 | PIPERIDINE AND PIPERAZINE DERIVATIVES | M'S SCIENCE CORPORATION (JP) | 2007-08-09 | — | — | WO | disclosed |