Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 5/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.33 |
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27785354 | 0.81 | ALOX5 (0.46) | ALOX5EPHX2AKR1C3HTR2CITGB3 | |
| SCHEMBL485135 | 0.79 | ALOX5 (0.45) | ALOX5EPHX2AKR1C3HTR2CITGB3 | |
| SCHEMBL3314951 | 0.77 | CYP1A2 (0.44) | ALOX5EPHX2AKR1C3 | |
| SCHEMBL3316474 | 0.77 | ALOX5 (0.44) | ALOX5EPHX2AKR1C3HTR2CITGB3 | |
| SCHEMBL4578235 | 0.77 | ALOX5 (0.44) | ALOX5EPHX2AKR1C3HTR2CITGB3 | |
| SCHEMBL1713095 | 0.77 | ALOX5 (0.44) | ALOX5EPHX2AKR1C3ITGB3ITGA2B | |
| SCHEMBL1713090 | 0.76 | ALOX5 (0.42) | ALOX5EPHX2AKR1C3HTR2CITGB3 | |
| SCHEMBL20300505 | 0.76 | ALDH1A1 (0.50) | ALOX5EPHX2AKR1C3POLBL3MBTL1 | |
| SCHEMBL1502093 | 0.76 | ALDH1A1 (0.52) | ALOX5EPHX2AKR1C3POLBL3MBTL1 | |
| SCHEMBL7365311 | 0.76 | CHRNB2 (0.57) | ALOX5POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |