Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 13/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9058813 | 0.82 | ALDH1A1 (0.40) | MAPTKMT2AALDH1A1GAA | |
| SCHEMBL1954999 | 0.82 | EPHX1 (0.42) | EPHX1ACHESMN1; SMN2NPC1RAB9A | |
| SCHEMBL526390 | 0.81 | KMT2A (0.41) | EPHX1ACHESMN1; SMN2NPC1RAB9A | |
| SCHEMBL4053495 | 0.81 | KMT2A (0.41) | EPHX1ACHESMN1; SMN2NPC1RAB9A | |
| SCHEMBL3685791 | 0.81 | EPHX1 (0.41) | EPHX1ACHESMN1; SMN2NPC1RAB9A | |
| SCHEMBL8303913 | 0.80 | EPHX1 (0.40) | EPHX1ACHESMN1; SMN2NPC1RAB9A | |
| SCHEMBL1739332 | 0.80 | MAPT (0.46) | EPHX1ACHESMN1; SMN2NPC1RAB9A | |
| SCHEMBL8327512 | 0.80 | EPHX1 (0.40) | EPHX1ACHESMN1; SMN2NPC1RAB9A | |
| SCHEMBL1536750 | 0.79 | KMT2A (0.42) | EPHX1ACHESMN1; SMN2NPC1RAB9A | |
| SCHEMBL4722847 | 0.78 | ALDH1A1 (0.44) | EPHX1ACHESMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245761-B1 | NERVOUS SYSTEM, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS | ELI LILLY AND COMPANY | 2001-06-12 | — | — | US | disclosed |
| EP-0789688-A4 | INDOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 1997-11-19 | — | — | EP | disclosed |
| EP-0789688-A1 | INDOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-08-20 | — | — | EP | disclosed |
| WO-1997009308-A1 | INDOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-03-13 | — | — | WO | disclosed |