Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | ME2 | P23368 | 1/20 | 0.39 |
| ▸ | ME1 | P48163 | 1/20 | 0.39 |
| ▸ | ME3 | Q16798 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7960226 | 0.81 | DRD2 (0.47) | MCHR1SMN1; SMN2RAB9AKMT2AMEN1 | |
| SCHEMBL7963783 | 0.79 | DRD2 (0.48) | MCHR1SMN1; SMN2RAB9AKMT2AMEN1 | |
| SCHEMBL7960846 | 0.73 | LMNA (0.43) | SMN1; SMN2HPGDKMT2AALDH1A1MEN1 | |
| SCHEMBL8092580 | 0.71 | GRM5 (0.53) | MCHR1GRM5HPGDKMT2AALDH1A1 | |
| SCHEMBL5799909 | 0.71 | MCHR1 (0.46) | MCHR1GRM5 | |
| SCHEMBL5443358 | 0.71 | F10 (0.65) | F10SMN1; SMN2HPGDRAB9AKMT2A | |
| SCHEMBL5443353 | 0.71 | F10 (0.65) | F10SMN1; SMN2HPGDRAB9AKMT2A | |
| SCHEMBL10291524 | 0.70 | NAMPT (0.59) | MCHR1GRM5HPGDKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL947439 | 0.69 | F10 (0.97) | F10 | |
| SCHEMBL14434754 | 0.68 | GRM5 (0.52) | MCHR1GRM5RAB9AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187774-B1 | N-PIPERAZINYLALKYLINDAZOLE DERIVATIVES; PSYCHOLOGICAL DISORDERS, SCHIZOPHRENIA; SIDE EFFECT REDUCTION | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-0885883-A1 | FUSED HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-12-23 | — | — | EP | disclosed |