Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728865 | 0.92 | ATM (0.55) | ATMPTGER4MAPTKMT2AMEN1 | |
| SCHEMBL4728742 | 0.86 | PTGER4 (0.62) | ATMPTGER4MAPTKMT2AMEN1 | |
| SCHEMBL4725234 | 0.85 | ELANE (0.49) | ATMPTGER4ELANEMAPTKMT2A | |
| SCHEMBL7976974 | 0.81 | NPY5R (0.50) | PTGER4NPY5RALDH1A1KDM4EHPGD | |
| SCHEMBL69334 | 0.76 | CA12 (0.56) | MAPTKMT2AMEN1CA12CA1 | |
| SCHEMBL7979591 | 0.76 | KDM4E (0.72) | MAPTKMT2AMEN1CASP3TRPV1 | |
| SCHEMBL21888553 | 0.75 | RAB9A (0.53) | PTGER4MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL4727898 | 0.73 | PTGER4 (0.53) | PTGER4ELANEMAPTKMT2AMEN1 | |
| SCHEMBL2080278 | 0.73 | ELANE (0.59) | ELANERAB9ANPC1LMNA | |
| SCHEMBL3830381 | 0.73 | CA12 (0.56) | MAPTKMT2AMEN1CASP3TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |