Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | KLK7 | P49862 | 2/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963528 | 0.86 | TDP1 (0.36) | NPSR1TDP1MEN1KMT2AMAPT | |
| SCHEMBL14090872 | 0.72 | NPSR1 (0.46) | NPSR1TDP1MEN1KMT2AMAPT | |
| SCHEMBL7977393 | 0.70 | ALB (0.40) | — | |
| SCHEMBL7973775 | 0.70 | ALB (0.40) | — | |
| SCHEMBL11990476 | 0.69 | FOLH1 (0.52) | NPSR1TDP1MEN1KMT2AMAPT | |
| SCHEMBL29072109 | 0.68 | KLK7 (0.60) | NPSR1TDP1MEN1KMT2AMAPT | |
| SCHEMBL29072115 | 0.68 | KLK7 (0.60) | NPSR1TDP1MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL20515013 | 0.68 | TDP1 (0.50) | NPSR1TDP1MEN1KMT2AMAPT | |
| SCHEMBL14090878 | 0.67 | NPSR1 (0.50) | NPSR1TDP1MEN1KMT2AMAPT | |
| SCHEMBL22972745 | 0.67 | KLK7 (0.59) | NPSR1TDP1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001005748-A1 | OLIGOMERIC AMINO ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | MONSANTO COMPANY (US) | 2001-01-25 | — | — | WO | disclosed |