Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GLS | O94925 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KLK7 | P49862 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963519 | 0.86 | NPSR1 (0.41) | TDP1NPSR1MAPTMEN1KMT2A | |
| SCHEMBL7977282 | 0.75 | TDP1 (0.40) | TDP1NPSR1MAPTMEN1KMT2A | |
| SCHEMBL7973780 | 0.70 | FOLH1 (0.41) | — | |
| SCHEMBL7973789 | 0.70 | FOLH1 (0.41) | — | |
| SCHEMBL7974823 | 0.66 | ALDH1A1 (0.47) | MEN1KMT2ACTSKGAAALDH1A1 | |
| SCHEMBL7963488 | 0.65 | ALDH1A1 (0.51) | TDP1NPSR1MAPTCTSKKDM4E | |
| SCHEMBL9632782 | 0.64 | LTA4H (0.47) | TDP1MAPTMEN1KMT2AKLK5 | |
| SCHEMBL9632783 | 0.64 | LTA4H (0.47) | TDP1MAPTMEN1KMT2AKLK5 | |
| SCHEMBL8058832 | 0.64 | FOLH1 (0.57) | — | |
| SCHEMBL11990476 | 0.64 | FOLH1 (0.52) | TDP1NPSR1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001005748-A1 | OLIGOMERIC AMINO ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | MONSANTO COMPANY (US) | 2001-01-25 | — | — | WO | disclosed |