Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | MMP1 | P03956 | 2/20 | 0.31 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | MMP3 | P08254 | 2/20 | 0.31 |
| ▸ | MMP9 | P14780 | 2/20 | 0.31 |
| ▸ | MMP8 | P22894 | 2/20 | 0.31 |
| ▸ | MMP12 | P39900 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16900024 | 0.78 | MME (0.53) | MMEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8228528 | 0.78 | CYP2C19 (0.44) | MMECYP2C19MT-CO2ALOX5ALDH1A1 | |
| SCHEMBL15998823 | 0.77 | MME (0.64) | MMEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL22952376 | 0.77 | MME (0.51) | MMEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL23757384 | 0.76 | MC4R (0.41) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL25632969 | 0.76 | MME (0.50) | MMEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL15264476 | 0.74 | KMT2A (0.33) | MMECYP2C19MT-CO2ALOX5ALDH1A1 | |
| SCHEMBL22956874 | 0.74 | MME (0.60) | MMEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL20078444 | 0.74 | MME (0.49) | MMEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL13003189 | 0.72 | ELANE (0.37) | CYP2C19MAPTLMNACYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154930-B1 | METHOD FOR THE PREPARATION OF BETA-SUBSTITUTED GAMMA-AMINO CARBOXYLIC ACIDS | SIEGFRIED LTD (CH) | 2018-04-18 | — | — | EP | disclosed |
| US-9745249-B2 | Method for the preparation of beta-substituted gamma-amino carboxylic acids | SIEGFRIED LTD. (CH) | 2017-08-29 | — | — | US | disclosed |
| US-9745249-B2 | Method for the preparation of beta-substituted gamma-amino carboxylic acids | SIEGFRIED LTD. (CH) | 2017-08-29 | — | — | US | disclosed |
| US-9737613-B2 | Colloid bonded medicinal compounds | B. BRAUN MELSUNGEN AG (DE) | 2017-08-22 | — | — | US | disclosed |
| US-20170114003-A1 | METHOD FOR THE PREPARATION OF BETA-SUBSTITUTED GAMMA-AMINO CARBOXYLIC ACIDS | SIEGFRIED LTD. (CH) | 2017-04-27 | — | — | US | disclosed |
| US-20170114003-A1 | METHOD FOR THE PREPARATION OF BETA-SUBSTITUTED GAMMA-AMINO CARBOXYLIC ACIDS | SIEGFRIED LTD. (CH) | 2017-04-27 | — | — | US | disclosed |
| WO-2015189068-A1 | METHOD FOR THE PREPARATION OF BETA-SUBSTITUTED GAMMA-AMINO CARBOXYLIC ACIDS | SIEGFRIED LTD. (CH) | 2015-12-17 | — | — | WO | disclosed |
| US-20150202307-A1 | Colloid Bonded Medicinal Compounds | B. BRAUN MELSUNGEN AG (DE) | 2015-07-23 | — | — | US | disclosed |
| US-8546112-B2 | Process for the stereoselective enzymatic hydrolysis of 5-methyl-3-nitromethyl-hexanoic acid ester | SANDOZ AG (CH) | 2013-10-01 | — | — | US | disclosed |
| US-8546112-B2 | Process for the stereoselective enzymatic hydrolysis of 5-methyl-3-nitromethyl-hexanoic acid ester | SANDOZ AG (CH) | 2013-10-01 | — | — | US | disclosed |
| EP-2294207-B1 | Process for the stereoselective enzymatic hydrolysis of 5-methyl-3-nitromethyl-hexanoic acid ester | SANDOZ AG (CH) | 2012-09-26 | — | — | EP | disclosed |
| US-20110165636-A1 | PROCESS FOR THE STEREOSELECTIVE ENZYMATIC HYDROLYSIS OF 5-METHYL-3-NITROMETHYL-HEXANOIC ACID ESTER | SANDOZ AG (CH) | 2011-07-07 | — | — | US | disclosed |
| US-20110165636-A1 | PROCESS FOR THE STEREOSELECTIVE ENZYMATIC HYDROLYSIS OF 5-METHYL-3-NITROMETHYL-HEXANOIC ACID ESTER | SANDOZ AG (CH) | 2011-07-07 | — | — | US | disclosed |
| WO-2009141362-A2 | PROCESS FOR THE STEREOSELECTIVE ENZYMATIC HYDROLYSIS OF 5-METHYL-3-NITROMETHYL-HEXANOIC ACID ESTER | SANDOZ AG (CH) | 2009-11-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170114003-A1 | METHOD FOR THE PREPARATION OF BETA-SUBSTITUTED GAMMA-AMINO CARBOXYLIC ACIDS | GLUL, GABRB2, GABRB1 | MME 1448/4885HDAC3 2073/4885HDAC4 3251/4885 |
| US-20150202307-A1 | Colloid Bonded Medicinal Compounds | ALB, EPCAM, SERPINA6 | MME 1237/4885HDAC3 3761/4885HDAC4 4622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.