SCHEMBL1104804

SCHEMBL1104804

Cc1ccc2nc(-c3ccccn3)c(-c3ccccn3)nc2c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.74
NPC1 O15118 3/20 0.74
ALDH1A1 P00352 10/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
NQO2 P16083 1/20 0.58
RAB9A P51151 3/20 0.56
PKM P14618 3/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
HPGD P15428 2/20 0.56
HSD17B10 Q99714 2/20 0.56
TP53 P04637 1/20 0.56
MAPT P10636 6/20 0.56
MEN1 O00255 4/20 0.56
KMT2A Q03164 4/20 0.56
METAP2 P50579 2/20 0.55
METAP1 P53582 2/20 0.55
CBFB Q13951 2/20 0.55
GAA P10253 3/20 0.51
USP2 O75604 1/20 0.46
ALOX15 P16050 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12927651 0.92 KDM4E (0.73) KDM4ENPC1ALDH1A1L3MBTL1NQO2
SCHEMBL4075083 0.85 KDM4E (1.00) KDM4ENPC1ALDH1A1L3MBTL1NQO2
SCHEMBL18880863 0.84 KDM4E (0.61) KDM4ENPC1ALDH1A1L3MBTL1NQO2
SCHEMBL7965339 0.83 KDM4E (0.81) KDM4ENPC1ALDH1A1L3MBTL1RAB9A
SCHEMBL7952005 0.82 KDM4E (0.68) KDM4ENPC1ALDH1A1L3MBTL1RAB9A
SCHEMBL2061612 0.81 KDM4E (0.70) KDM4ENPC1ALDH1A1L3MBTL1RAB9A
SCHEMBL14063447 0.81 KDM4E (0.66) KDM4ENPC1ALDH1A1L3MBTL1RAB9A
SCHEMBL7963689 0.80 KDM4E (0.75) KDM4ENPC1ALDH1A1L3MBTL1NQO2
SCHEMBL19092285 0.79 KDM4E (0.64) KDM4ENPC1ALDH1A1L3MBTL1PKM
SCHEMBL20061276 0.77 KDM4E (0.53) KDM4ENPC1ALDH1A1L3MBTL1NQO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 369 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11691983-B2 Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes IDEMITSU KOSAN CO., LTD. (JP) 2023-07-04 US disclosed
US-11691983-B2 Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes IDEMITSU KOSAN CO., LTD. (JP) 2023-07-04 US disclosed
US-10833281-B2 Organic electroluminescence composition, material for organic electroluminescence element, solution of material for organic electroluminescence element, and organic electroluminescence element IDEMITSU KOSAN CO., LTD. (JP) 2020-11-10 US disclosed
US-10763442-B2 Compound, organic electroluminescent element material using same, organic electroluminescent element using this material, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2020-09-01 US disclosed
US-10707434-B2 Organic electroluminescence element, and material for organic electroluminescence element IDEMITSU KOSAN CO., LTD. (JP) 2020-07-07 US disclosed
EP-2790239-B1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO (JP) 2020-02-05 EP disclosed
US-20190161497-A1 SPECIFICALLY SUBSTITUTED BENZOFURO- AND BENZOTHIENOQUINOLINES FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO., LTD. (JP) 2019-05-30 US disclosed
US-20190148649-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT MATERIAL USING SAME, ORGANIC ELECTROLUMINESCENT ELEMENT USING THIS MATERIAL, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2019-05-16 US disclosed
US-10230057-B2 Biscarbazole derivatives and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2019-03-12 US disclosed
US-20190019972-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2019-01-17 US disclosed
US-7399432-B2 Charge transport compositions and electronic devices made with such compositions E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-07-15 US disclosed
US-20080076942-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2008-03-27 US disclosed
US-20080076942-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2008-03-27 US disclosed
US-20070273270-A1 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2007-11-29 US disclosed
US-20070273270-A1 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2007-11-29 US disclosed
US-20070275266-A1 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2007-11-29 US disclosed
US-20070275266-A1 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2007-11-29 US disclosed
US-20070267968-A1 ELECTRONIC DEVICES MADE WITH ELECTRON TRANSPORT AND/OR ANTI-QUENCHING LAYERS LECLOUX DANIEL D 2007-11-22 US disclosed
US-7265378-B2 Electronic devices made with electron transport and/or anti-quenching layers E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-09-04 US disclosed
US-7265378-B2 Electronic devices made with electron transport and/or anti-quenching layers E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-09-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080076942-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME TYR, MAOA, DDC KDM4E 156/4885NPC1 4722/4885ALDH1A1 119/4885
US-10833281-B2 Organic electroluminescence composition, material for organic electroluminescence element, solution of material for organic electroluminescence element, and organic electroluminescence element SLCO4C1, SLCO2A1, SLCO1A2 KDM4E 3030/4885NPC1 648/4885ALDH1A1 2178/4885
US-20190019972-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT LEF1, L1CAM, AGO2 KDM4E 3248/4885NPC1 2824/4885ALDH1A1 816/4885
US-11691983-B2 Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes KCNQ2, KCNQ1, KCNQ4 KDM4E 962/4885NPC1 2663/4885ALDH1A1 865/4885
US-20190148649-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT MATERIAL USING SAME, ORGANIC ELECTROLUMINESCENT ELEMENT USING THIS MATERIAL, AND ELECTRONIC DEVICE OR10J3, RER1, L1CAM KDM4E 2101/4885NPC1 2392/4885ALDH1A1 1740/4885
US-10230057-B2 Biscarbazole derivatives and organic electroluminescence device employing the same EED, GABRE, EML4 KDM4E 312/4885NPC1 4486/4885ALDH1A1 412/4885
US-10707434-B2 Organic electroluminescence element, and material for organic electroluminescence element LEF1, L1CAM, AGO2 KDM4E 3248/4885NPC1 2824/4885ALDH1A1 816/4885
US-10763442-B2 Compound, organic electroluminescent element material using same, organic electroluminescent element using this material, and electronic device OR10J3, RER1, L1CAM KDM4E 2101/4885NPC1 2392/4885ALDH1A1 1740/4885
US-20190161497-A1 SPECIFICALLY SUBSTITUTED BENZOFURO- AND BENZOTHIENOQUINOLINES FOR ORGANIC LIGHT EMITTING DIODES KCNQ2, KCNQ1, KCNQ4 KDM4E 962/4885NPC1 2663/4885ALDH1A1 865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.