Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | AKT1 | P31749 | 3/20 | 0.38 |
| ▸ | AKT2 | P31751 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963780 | 0.83 | AKT1 (0.37) | MAPTLMNATP53KMT2AAKT1 | |
| Mandelic Acid SCHEMBL7963777 | 0.79 | MAPT (0.38) | MAPTLMNAALDH1A1TP53KMT2A | |
| SCHEMBL23442934 | 0.69 | AKT1 (0.44) | MAPTLMNAALDH1A1TP53KMT2A | |
| SCHEMBL25171674 | 0.64 | HDAC4 (0.49) | LMNAALDH1A1TP53AKT1AKT2 | |
| SCHEMBL24163550 | 0.62 | KMT2A (0.84) | MAPTLMNAALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL7953572 | 0.61 | KMT2A (0.54) | MAPTLMNAALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL29891579 | 0.61 | HPGDS (0.53) | TP53KMT2APOLBMEN1 | |
| Maleic Acid SCHEMBL7967347 | 0.60 | DRD4 (0.53) | — | |
| SCHEMBL20444530 | 0.58 | KMT2A (0.76) | MAPTLMNAALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL20437921 | 0.58 | KMT2A (0.94) | MAPTLMNAALDH1A1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242450-B1 | SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| EP-0976746-A1 | 5-HT1F antagonists | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |