Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 3/20 | 0.37 |
| ▸ | AKT2 | P31751 | 3/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 3/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963779 | 0.83 | MAPT (0.41) | AKT1AKT2MAPTTP53MEN1 | |
| Mandelic Acid SCHEMBL7963777 | 0.77 | MAPT (0.38) | AKT1AKT2MAPTTP53MEN1 | |
| SCHEMBL23442934 | 0.64 | AKT1 (0.44) | AKT1AKT2MAPTTP53KMT2A | |
| SCHEMBL25171674 | 0.64 | HDAC4 (0.49) | AKT1AKT2TP53LMNA | |
| SCHEMBL7962234 | 0.62 | HTR1A (0.36) | AKT1AKT2 | |
| SCHEMBL7953579 | 0.61 | CCR1 (0.41) | MEN1KMT2ALMNA | |
| SCHEMBL29891579 | 0.60 | HPGDS (0.53) | TP53THRBMEN1KMT2A | |
| SCHEMBL3714809 | 0.60 | HPGDS (0.53) | TP53THRBMEN1KMT2A | |
| SCHEMBL9074787 | 0.60 | HTR1A (0.52) | MCHR1 | |
| SCHEMBL24870232 | 0.58 | HTR3A (0.49) | BCHEMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242450-B1 | SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| EP-0976746-A1 | 5-HT1F antagonists | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |