Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329854 | 0.91 | DHODH (0.36) | KDM4EALDH1A1GAAMAPTRAB9A | |
| SCHEMBL7967502 | 0.90 | GAA (0.32) | KDM4EALDH1A1GAAMAPTRAB9A | |
| SCHEMBL7952832 | 0.89 | HCRTR1 (0.34) | KDM4EALDH1A1GAAMAPTRAB9A | |
| SCHEMBL7952345 | 0.88 | CYP11B2 (0.34) | DHODH | |
| SCHEMBL7952437 | 0.86 | DHODH (0.34) | ALDH1A1MAPTDHODH | |
| SCHEMBL7961833 | 0.85 | DHODH (0.38) | KDM4EALDH1A1MAPTRAB9ADHODH | |
| SCHEMBL7964888 | 0.85 | CYP11B2 (0.32) | KDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL7964306 | 0.82 | MAPT (0.32) | MAPTDHODH | |
| SCHEMBL7965413 | 0.82 | NPC1 (0.32) | KDM4EALDH1A1RAB9A | |
| SCHEMBL7967150 | 0.82 | POLB (0.33) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207675-B1 | FOR PROPHYLAXIS AND THERAPY OF DISEASES IN WHICH ARE INVOLVED VIRUSES OF THE HERPES FAMILY AND/OR CYTOKINES IN PARTICULAR TUMOR NERCOSIS FACTOR-ALPHA | RHONE-POULENC RORER S.A. (FR) | 2001-03-27 | — | — | US | claimed |
| US-6207675-B1 | FOR PROPHYLAXIS AND THERAPY OF DISEASES IN WHICH ARE INVOLVED VIRUSES OF THE HERPES FAMILY AND/OR CYTOKINES IN PARTICULAR TUMOR NERCOSIS FACTOR-ALPHA | RHONE-POULENC RORER S.A. (FR) | 2001-03-27 | — | — | US | disclosed |