Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 3/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.34 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.31 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.31 |
| ▸ | SLC6A15 | Q9H2J7 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963785 | 0.89 | KDM4E (0.32) | ALDH1A1KDM4EGAARAB9AMAPT | |
| SCHEMBL7967763 | 0.89 | HCRTR1 (0.35) | HCRTR1HCRTR2KCNMA1IDO1HTR2A | |
| SCHEMBL8329854 | 0.88 | DHODH (0.36) | ALDH1A1KDM4EGAARAB9AMAPT | |
| SCHEMBL7967502 | 0.87 | GAA (0.32) | ALDH1A1KDM4EGAARAB9AMAPT | |
| SCHEMBL7965862 | 0.87 | IDO1 (0.35) | IDO1ALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL7963830 | 0.86 | DHODH (0.36) | IDO1ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL7961242 | 0.85 | IDO1 (0.34) | IDO1KDM4ERAB9AMAPTMEN1 | |
| SCHEMBL7952188 | 0.83 | IDO1 (0.35) | IDO1KDM4EHSP90AA1HSP90B1TDP2 | |
| SCHEMBL7964888 | 0.82 | CYP11B2 (0.32) | KCNMA1ALDH1A1KDM4ERAB9AMAPT | |
| SCHEMBL7964071 | 0.81 | CYP11B2 (0.39) | HTR2AHTR2CALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207675-B1 | FOR PROPHYLAXIS AND THERAPY OF DISEASES IN WHICH ARE INVOLVED VIRUSES OF THE HERPES FAMILY AND/OR CYTOKINES IN PARTICULAR TUMOR NERCOSIS FACTOR-ALPHA | RHONE-POULENC RORER S.A. (FR) | 2001-03-27 | — | — | US | claimed |
| US-6207675-B1 | FOR PROPHYLAXIS AND THERAPY OF DISEASES IN WHICH ARE INVOLVED VIRUSES OF THE HERPES FAMILY AND/OR CYTOKINES IN PARTICULAR TUMOR NERCOSIS FACTOR-ALPHA | RHONE-POULENC RORER S.A. (FR) | 2001-03-27 | — | — | US | disclosed |