Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329854 | 0.91 | DHODH (0.36) | GAAKDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL7963785 | 0.90 | KDM4E (0.32) | GAAKDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL7963714 | 0.88 | CYP11B2 (0.34) | KDM4ERECQL | |
| SCHEMBL7952832 | 0.87 | HCRTR1 (0.34) | GAAHPGDKDM4EALDH1A1MAPT | |
| SCHEMBL7965560 | 0.86 | HPGD (0.32) | HPGDALDH1A1 | |
| SCHEMBL7964888 | 0.85 | CYP11B2 (0.32) | KDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL7962627 | 0.84 | DHODH (0.37) | HPGDALDH1A1MAPTRAB9A | |
| SCHEMBL7964894 | 0.82 | MAPT (0.32) | HPGDMAPT | |
| SCHEMBL7953686 | 0.82 | POLB (0.31) | HPGD | |
| SCHEMBL7962248 | 0.82 | CYP11B2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207675-B1 | FOR PROPHYLAXIS AND THERAPY OF DISEASES IN WHICH ARE INVOLVED VIRUSES OF THE HERPES FAMILY AND/OR CYTOKINES IN PARTICULAR TUMOR NERCOSIS FACTOR-ALPHA | RHONE-POULENC RORER S.A. (FR) | 2001-03-27 | — | — | US | claimed |
| US-6207675-B1 | FOR PROPHYLAXIS AND THERAPY OF DISEASES IN WHICH ARE INVOLVED VIRUSES OF THE HERPES FAMILY AND/OR CYTOKINES IN PARTICULAR TUMOR NERCOSIS FACTOR-ALPHA | RHONE-POULENC RORER S.A. (FR) | 2001-03-27 | — | — | US | disclosed |