Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 7/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7949172 | 0.86 | DRD2 (0.61) | DRD2DRD4DRD3MCHR1 | |
| SCHEMBL10595036 | 0.86 | SLC18A3 (0.61) | DRD2SLC18A3 | |
| SCHEMBL7957372 | 0.85 | DRD2 (0.51) | DRD2DRD4DRD3NPY1RKDM4E | |
| SCHEMBL7961389 | 0.84 | NPY1R (0.50) | HSD17B10DRD2DRD4DRD3NPY1R | |
| SCHEMBL7957636 | 0.83 | NPY1R (0.47) | HSD17B10DRD2DRD4DRD3NPY1R | |
| SCHEMBL7949175 | 0.83 | DRD2 (0.48) | DRD2DRD4DRD3KDM4EMCHR1 | |
| SCHEMBL7959172 | 0.82 | DRD2 (0.62) | DRD2DRD4DRD3NPY1RHRH3 | |
| SCHEMBL7957439 | 0.81 | DRD2 (0.55) | DRD2DRD4DRD3MCHR1SLC18A3 | |
| SCHEMBL10759929 | 0.81 | KCNH2 (0.64) | DRD2DRD4 | |
| SCHEMBL7949328 | 0.80 | DRD2 (0.46) | DRD2DRD4DRD3NPY1RKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187774-B1 | N-PIPERAZINYLALKYLINDAZOLE DERIVATIVES; PSYCHOLOGICAL DISORDERS, SCHIZOPHRENIA; SIDE EFFECT REDUCTION | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-0885883-A1 | FUSED HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-12-23 | — | — | EP | disclosed |