Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 4/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.42 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.42 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961389 | 0.89 | NPY1R (0.50) | NPY1RHSD17B10DRD2DRD4DRD3 | |
| SCHEMBL7957372 | 0.83 | DRD2 (0.51) | NPY1RDRD2DRD4DRD3KDM4E | |
| SCHEMBL7963919 | 0.83 | HSD17B10 (0.53) | NPY1RHSD17B10DRD2DRD4DRD3 | |
| SCHEMBL7949172 | 0.82 | DRD2 (0.61) | DRD2DRD4DRD3MCHR1 | |
| SCHEMBL7949175 | 0.81 | DRD2 (0.48) | DRD2DRD4DRD3KDM4ETSHR | |
| SCHEMBL7957657 | 0.81 | DRD2 (0.49) | NPY1RHSD17B10DRD2KDM4ETSHR | |
| SCHEMBL7961179 | 0.81 | DRD2 (0.47) | DRD2DRD4DRD3POLBOPRL1 | |
| SCHEMBL7961467 | 0.80 | HTR4 (0.48) | NPY1RHSD17B10DRD2DRD4DRD3 | |
| SCHEMBL7961109 | 0.78 | ALDH1A1 (0.42) | NPY1RDRD2DRD4DRD3KDM4E | |
| SCHEMBL17731192 | 0.78 | OPRL1 (0.50) | SMN1; SMN2OPRL1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187774-B1 | N-PIPERAZINYLALKYLINDAZOLE DERIVATIVES; PSYCHOLOGICAL DISORDERS, SCHIZOPHRENIA; SIDE EFFECT REDUCTION | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-0885883-A1 | FUSED HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-12-23 | — | — | EP | disclosed |