Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7964041 | 0.93 | POLB (0.47) | ARNPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL7975321 | 0.93 | AR (0.48) | ARNPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL7964013 | 0.90 | AR (0.46) | ARNPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL7974397 | 0.90 | SMN1; SMN2 (0.50) | ARNPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL7974453 | 0.88 | NPC1 (0.50) | ARNPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL7980183 | 0.87 | AR (0.46) | ARNPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL7975380 | 0.86 | LMNA (0.47) | ARNPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL7977473 | 0.86 | RAB9A (0.48) | ARNPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL7977629 | 0.86 | SMN1; SMN2 (0.48) | ARNPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL7974298 | 0.85 | POLB (0.50) | ARNPC1RAB9APOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | claimed |
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |