Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.48 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19798040 | 0.94 | L3MBTL1 (0.57) | L3MBTL1KMT2ALMNAGAATDP1 | |
| SCHEMBL19798036 | 0.94 | L3MBTL1 (0.57) | L3MBTL1KMT2ALMNAGAATDP1 | |
| SCHEMBL19798038 | 0.94 | L3MBTL1 (0.57) | L3MBTL1KMT2ALMNAGAATDP1 | |
| SCHEMBL19798037 | 0.94 | L3MBTL1 (0.57) | L3MBTL1KMT2ALMNAGAATDP1 | |
| SCHEMBL24819498 | 0.93 | LMNA (0.69) | L3MBTL1KMT2ALMNAGAATDP1 | |
| SCHEMBL4618083 | 0.91 | CYP19A1 (0.65) | L3MBTL1KMT2ATDP1ATMCYP19A1 | |
| SCHEMBL789755 | 0.91 | SMN1; SMN2 (0.60) | L3MBTL1KMT2ALMNATDP1ATM | |
| SCHEMBL28183303 | 0.83 | LMNA (0.59) | L3MBTL1KMT2ALMNAGAATDP1 | |
| SCHEMBL414384 | 0.82 | SENP1 (0.59) | L3MBTL1KMT2ATDP1ATMCYP19A1 | |
| SCHEMBL19599393 | 0.81 | L3MBTL1 (0.46) | L3MBTL1KMT2ALMNAGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180022996-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| WO-2009120235-A1 | MONOMER SOLUTION FOR PRODUCING POLYCARBONATE | SABIC INNOVATIVE PLASTICS IP BV (NL) | 2009-10-01 | — | — | WO | disclosed |
| US-6274583-B1 | Alpha 1a adrenergic receptor antagonists | MERCK & CO., INC. | 2001-08-14 | — | — | US | disclosed |
| US-5977115-A | Alpha 1a adrenergic receptor antagonists | MERCK & CO., INC. (US) | 1999-11-02 | — | — | US | disclosed |
| EP-0833637-A4 | ALPHA 1a ADRENERGIC RECEPTOR ANTAGONIST | MERCK & CO INC (US) | 1998-07-08 | — | — | EP | disclosed |
| EP-0833637-A1 | ALPHA 1a ADRENERGIC RECEPTOR ANTAGONIST | Merck & Co., Inc. (US) | 1998-04-08 | — | — | EP | disclosed |
| US-5661163-A | TREATMENT OF BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC. (US) | 1997-08-26 | — | — | US | disclosed |
| WO-1996040136-A1 | ALPHA 1a ADRENERGIC RECEPTOR ANTAGONIST | MERCK & CO., INC. (US) | 1996-12-19 | — | — | WO | disclosed |