Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 14/20 | 0.73 |
| ▸ | NPC1 | O15118 | 13/20 | 0.73 |
| ▸ | MEN1 | O00255 | 8/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.73 |
| ▸ | CASP3 | P42574 | 5/20 | 0.61 |
| ▸ | SENP7 | Q9BQF6 | 5/20 | 0.61 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.61 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | NQO2 | P16083 | 1/20 | 0.60 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3503370 | 0.89 | NPC1 (0.84) | RAB9ANPC1MEN1KMT2ATDP1 | |
| SCHEMBL8420152 | 0.84 | NPC1 (0.72) | RAB9ANPC1MEN1KMT2ATDP1 | |
| SCHEMBL2681024 | 0.84 | NPC1 (1.00) | RAB9ANPC1MEN1KMT2ATDP1 | |
| SCHEMBL2230642 | 0.84 | NPC1 (0.77) | RAB9ANPC1MEN1KMT2ATDP1 | |
| SCHEMBL26885202 | 0.84 | NPC1 (0.77) | RAB9ANPC1MEN1KMT2ATDP1 | |
| SCHEMBL2229842 | 0.84 | NPC1 (0.76) | RAB9ANPC1MEN1KMT2ATDP1 | |
| SCHEMBL23844169 | 0.84 | LMNA (0.76) | RAB9ANPC1MEN1KMT2ATDP1 | |
| SCHEMBL8081011 | 0.83 | DEGS1 (0.82) | RAB9ANPC1MEN1KMT2ATDP1 | |
| SCHEMBL3660083 | 0.83 | NPC1 (0.74) | RAB9ANPC1MEN1KMT2ATDP1 | |
| SCHEMBL13863923 | 0.83 | MEN1 (0.71) | RAB9ANPC1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218393-B1 | IN THERAPY OF MULTIDRUG RESISTANT CANCERS, FOR EXAMPLE TO POTENTIATE CYTOTOXICITY OF CANCER DRUG | XENOVA LIMITED (GB) | 2001-04-17 | — | — | US | disclosed |