Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 14/20 | 0.72 |
| ▸ | RAB9A | P51151 | 14/20 | 0.72 |
| ▸ | MEN1 | O00255 | 10/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | APEX1 | P27695 | 1/20 | 0.66 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.60 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.60 |
| ▸ | CASP3 | P42574 | 4/20 | 0.60 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.60 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.60 |
| ▸ | NQO2 | P16083 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3503370 | 0.92 | NPC1 (0.84) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL679200 | 0.90 | DEGS1 (0.74) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL13023026 | 0.87 | CASP3 (0.64) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL26885202 | 0.87 | NPC1 (0.77) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL2229842 | 0.86 | NPC1 (0.76) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL3660083 | 0.85 | NPC1 (0.74) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL8081011 | 0.85 | DEGS1 (0.82) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL7964170 | 0.84 | RAB9A (0.73) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL9389092 | 0.84 | NPC1 (0.69) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL2230642 | 0.84 | NPC1 (0.77) | NPC1RAB9AMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573573-B1 | MESOGENIC GLYCIDYL AMINES | DOW CHEMICAL CO (US) | 1999-09-29 | — | — | EP | disclosed |
| US-5360884-A | Coatings, adhesives, moldings, laminates and encapsulation | THE DOW CHEMICAL COMPANY (US) | 1994-11-01 | — | — | US | disclosed |
| EP-0573573-A1 | MESOGENIC GLYCIDYL AMINES | THE DOW CHEMICAL COMPANY (US) | 1993-12-15 | — | — | EP | disclosed |
| US-5262509-A | Curable coatings | THE DOW CHEMICAL COMPANY (US) | 1993-11-16 | — | — | US | disclosed |
| WO-1992015630-A2 | MESOGENIC GLYCIDYL AMINES | THE DOW CHEMICAL COMPANY (US) | 1992-09-17 | — | — | WO | disclosed |
| EP-0194884-B1 | ANTICONVULSANT AGENTS | ELI LILLY AND COMPANY (US) | 1989-03-08 | — | — | EP | disclosed |
| US-4632939-A | P-AMINOBENZAMIDES | ELI LILLY AND COMPANY (US) | 1986-12-30 | — | — | US | disclosed |
| EP-0194884-A1 | Anticonvulsant agents | ELI LILLY AND COMPANY (US) | 1986-09-17 | — | — | EP | disclosed |