Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.41 |
| ▸ | CBLB | Q13191 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8687760 | 0.87 | SMN1; SMN2 (0.45) | MAPTSMN1; SMN2NPY5RRAB9AALDH1A1 | |
| SCHEMBL8721044 | 0.87 | ALDH1A1 (0.46) | MAPTSMN1; SMN2NPY5RRAB9AALDH1A1 | |
| SCHEMBL8725049 | 0.87 | MAPT (0.53) | MAPTSMN1; SMN2NPY5RRAB9AALDH1A1 | |
| SCHEMBL8574398 | 0.82 | ADORA2A (0.50) | MAPTALDH1A1ADORA2AADORA1KDM4E | |
| SCHEMBL7963938 | 0.82 | ALDH1A1 (0.42) | MAPTALDH1A1CYP3A4HSD17B10IRAK4 | |
| SCHEMBL8725772 | 0.81 | CD38 (0.47) | SMN1; SMN2ALDH1A1CYP3A4HSD17B10CBLB | |
| SCHEMBL8725888 | 0.80 | CBLB (0.45) | RAB9AALDH1A1CYP3A4HSD17B10ROCK1 | |
| SCHEMBL8725981 | 0.78 | XPO1 (0.40) | ALDH1A1CYP3A4HSD17B10POLBCBLB | |
| SCHEMBL8721733 | 0.78 | BUB1 (0.43) | SMN1; SMN2RAB9AALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL54805 | 0.76 | MAPT (0.65) | MAPTNPY5RRAB9AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271372-B1 | REACTING HETEROAROMATIC HALOGEN COMPOUNDS WITH CARBON MONOXIDE AND AROMATIC AMINES IN THE PRESENCE OF A COMPLEX OF PALLADIUM WITH A TRIPHENYLPHOSPHINE AND A BASE OTHER THAN AN AMINE. | LONZA AG (CH) | 2001-08-07 | — | — | US | disclosed |
| EP-0806415-B1 | Process for the preparation of arylamides of heteroaromatic carboxylic acids | LONZA AG (CH) | 2000-02-16 | — | — | EP | disclosed |
| US-5900484-A | FROM HETEROAROMATIC HALOGEN COMPOUNDS AND AROMATIC AMINES AND CARBON MONOXIDE WITH PALLADIUM PHOSPHINE COMPLEX | LONZA AG (CH) | 1999-05-04 | — | — | US | disclosed |
| US-5892032-A | Process for the preparation of arylamides of heteroaromatic carboxylic acids | LONZA AG (CH) | 1999-04-06 | — | — | US | disclosed |
| US-5707933-A | PLANT GROWTH REGULATORS AND ANTIGROWTH AGENTS | AMERICAN CYANAMID COMPANY (US) | 1998-01-13 | — | — | US | disclosed |
| US-5707932-A | PLANT GROWTH REGULATORS; PRE- AND POSTEMERGENCE | AMERICAN CYANAMID COMPANY (US) | 1998-01-13 | — | — | US | disclosed |
| EP-0806415-A1 | Process for the preparation of arylamides of heteroaromatic carboxylic acids | LONZA AG (CH) | 1997-11-12 | — | — | EP | disclosed |
| EP-0665841-B1 | HERBICIDAL PYRAZOLYLOXY-PICOLINAMIDES | SHELL INT RESEARCH (NL) | 1996-07-17 | — | — | EP | disclosed |
| EP-0665841-A1 | HERBICIDAL PYRAZOLYLOXY-PICOLINAMIDES. | SHELL INT RESEARCH (NL) | 1995-08-09 | — | — | EP | disclosed |
| WO-1994008991-A1 | HERBICIDAL PYRAZOLYLOXY-PICOLINAMIDES | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1994-04-28 | — | — | WO | disclosed |