Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 2/20 | 0.47 |
| ▸ | CBLB | Q13191 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8725981 | 0.91 | XPO1 (0.40) | CD38CBLBSCN10ACYP3A4ALDH1A1 | |
| SCHEMBL8725888 | 0.91 | CBLB (0.45) | CBLBTSHRSCN2ASCN10ANTRK1 | |
| SCHEMBL8721044 | 0.90 | ALDH1A1 (0.46) | CBLBSMN1; SMN2CYP3A4ALDH1A1HSD17B10 | |
| SCHEMBL8721733 | 0.88 | BUB1 (0.43) | CD38CBLBSMN1; SMN2CYP3A4ALDH1A1 | |
| SCHEMBL8721042 | 0.85 | LMNA (0.49) | SMN1; SMN2CYP3A4HSD17B10CYP1A2CYP2C9 | |
| SCHEMBL8725972 | 0.84 | SMN1; SMN2 (0.45) | CBLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL8721806 | 0.82 | CD38 (0.49) | CD38CBLBTSHRSCN2ASCN10A | |
| SCHEMBL7964413 | 0.81 | MAPT (0.50) | CBLBSMN1; SMN2KDRCYP3A4ALDH1A1 | |
| SCHEMBL8720597 | 0.79 | KMT2A (0.39) | CBLBNTRK1CYP3A4ALDH1A1HSD17B10 | |
| SCHEMBL8720573 | 0.79 | KMT2A (0.39) | CBLBSCN10ACYP3A4ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700391-B1 | HERBICIDAL COMPOUNDS | SHELL INT RESEARCH (NL) | 1998-10-21 | — | — | EP | claimed |