Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.38 |
| ▸ | ULK1 | O75385 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8720573 | 0.85 | KMT2A (0.39) | ALDH1A1ADORA2AADORA1SCN9ASCN10A | |
| SCHEMBL8574398 | 0.83 | ADORA2A (0.50) | ALDH1A1ADORA2AADORA1MAPTKMT2A | |
| SCHEMBL7964413 | 0.82 | MAPT (0.50) | ALDH1A1ADORA2AADORA1MAPTKMT2A | |
| SCHEMBL5553184 | 0.75 | ADORA2A (0.49) | ALDH1A1ADORA2AADORA1KMT2ATGFBR1 | |
| SCHEMBL6615519 | 0.74 | ALDH1A1 (0.40) | ALDH1A1ADORA2AADORA1EGLN2KMT2A | |
| SCHEMBL7953446 | 0.74 | KMT2A (0.50) | ALDH1A1ADORA2AADORA1MAPTKMT2A | |
| SCHEMBL6613473 | 0.73 | ADORA2A (0.44) | ALDH1A1ADORA2AADORA1KMT2ATGFBR1 | |
| SCHEMBL6613296 | 0.73 | ADORA2A (0.48) | ALDH1A1ADORA2AADORA1KMT2ATGFBR1 | |
| SCHEMBL9017235 | 0.73 | SCN9A (0.46) | SCN9ASCN10AKMT2AULK1 | |
| SCHEMBL6614783 | 0.72 | ADORA2A (0.41) | ALDH1A1ADORA2AADORA1MAPTEGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7285962-A | — | — | None | — | — | JP | disclosed |
| US-6271372-B1 | REACTING HETEROAROMATIC HALOGEN COMPOUNDS WITH CARBON MONOXIDE AND AROMATIC AMINES IN THE PRESENCE OF A COMPLEX OF PALLADIUM WITH A TRIPHENYLPHOSPHINE AND A BASE OTHER THAN AN AMINE. | LONZA AG (CH) | 2001-08-07 | — | — | US | disclosed |
| US-5900484-A | FROM HETEROAROMATIC HALOGEN COMPOUNDS AND AROMATIC AMINES AND CARBON MONOXIDE WITH PALLADIUM PHOSPHINE COMPLEX | LONZA AG (CH) | 1999-05-04 | — | — | US | disclosed |
| JP-H07285962-A | PYRIDINECARBOXYLIC ACID AMIDE DERIVATIVE | NISSAN CHEM IND LTD | 1995-10-31 | — | — | JP | disclosed |