SCHEMBL7964480

SCHEMBL7964480

COc1ccc(C(C)C(=O)NC2(C(=O)O)CCC(C)C(C)C2)c(C)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCR5 P32302 2/20 0.38
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
APOBEC3A P31941 1/20 0.34
APOBEC3G Q9HC16 1/20 0.34
SMYD3 Q9H7B4 1/20 0.34
LPAR1 Q92633 2/20 0.33
TAS1R3 Q7RTX0 1/20 0.33
TAS1R1 Q7RTX1 1/20 0.33
POLB P06746 1/20 0.33
P2RX7 Q99572 1/20 0.32
PTGS2 P35354 3/20 0.32
PTGS1 P23219 2/20 0.32
AKR1C3 P42330 2/20 0.32
AKR1C2 P52895 2/20 0.32
CDC42 P60953 1/20 0.32
RAC1 P63000 1/20 0.32
CYP1A2 P05177 1/20 0.32
TSHR P16473 1/20 0.32
SLC22A6 Q4U2R8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7960346 0.92 ALDH1A1 (0.34) CXCR5ALDH1A1HPGDAPOBEC3AAPOBEC3G
SCHEMBL7950122 0.89 CXCR5 (0.39) CXCR5ALDH1A1HPGDSMYD3LPAR1
SCHEMBL7964128 0.87 CXCR5 (0.37) CXCR5ALDH1A1HPGDAPOBEC3AAPOBEC3G
SCHEMBL7961986 0.85 CXCR5 (0.41) CXCR5SMYD3LPAR1P2RX7PTGS2
SCHEMBL7958362 0.85 CXCR5 (0.39) CXCR5ALDH1A1SMYD3PTGS2PTGS1
SCHEMBL7961902 0.84 GPR88 (0.42) ALDH1A1SMYD3POLBPTGS2PTGS1
SCHEMBL7958053 0.84 CXCR5 (0.41) CXCR5ALDH1A1HPGDLPAR1P2RX7
SCHEMBL7958019 0.84 MEN1 (0.39) CXCR5SMYD3MEN1KMT2ANPC1
SCHEMBL7964342 0.84 CXCR5 (0.38) CXCR5ALDH1A1SMYD3PTGS2PTGS1
SCHEMBL7959968 0.84 LPAR1 (0.42) ALDH1A1LPAR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6172255-B1 INSECTICIDES; MITICIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-01-09 US disclosed
US-5830826-A Alkoxy-alkyl-substituted 1H-3-aryl-pyrrolidine-2, 4-diones used as herbicicides and pesticides BAYER AKTIENGESELLSCHAFT (DE) 1998-11-03 US disclosed