Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23411619 | 0.82 | MPO (0.49) | MPORAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2859330 | 0.82 | MPO (0.67) | MPORAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL374150 | 0.82 | SOS1 (0.51) | MPORAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14157509 | 0.82 | MPO (0.49) | MPORAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL20134872 | 0.82 | MPO (0.49) | MPORAB9ANPC1ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL31150133 | 0.81 | MPO (0.48) | MPORAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL23411408 | 0.79 | MPO (0.46) | MPORAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2856494 | 0.79 | HTR2C (0.47) | MPOLMNAMEN1KMT2AROCK2 | |
| SCHEMBL373400 | 0.78 | MPO (0.54) | MPORAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7954385 | 0.77 | RAB9A (0.62) | MPORAB9ANPC1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303627-B1 | FOR THERAPY OF PHYSIOLOGICAL AND PSYCHOLOGICAL DISORDERS | ELI LILLY AND COMPANY | 2001-10-16 | — | — | US | disclosed |
| EP-0965587-A1 | Tetrahydropyridinyl- and piperidinyl Inhibitors of serotonin reuptake | ELI LILLY AND COMPANY (US) | 1999-12-22 | — | — | EP | disclosed |