Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7415153 | 0.90 | MAPT (0.44) | USP2CASP1HSD17B10MAPTTP53 | |
| SCHEMBL7958034 | 0.89 | MEN1 (0.44) | USP2CASP1HSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL7959855 | 0.88 | LMNA (0.44) | MAPTTP53SMN1; SMN2RAB9ALMNA | |
| SCHEMBL7418952 | 0.88 | RAB9A (0.44) | SMN1; SMN2RAB9ALMNANPC1GAA | |
| SCHEMBL7411535 | 0.86 | SMN1; SMN2 (0.55) | MAPTSMN1; SMN2RAB9ALMNANPC1 | |
| SCHEMBL7416321 | 0.86 | MAPT (0.47) | MAPTSMN1; SMN2RAB9ALMNANPC1 | |
| SCHEMBL7961855 | 0.86 | SMN1; SMN2 (0.55) | HSD17B10MAPTTP53SMN1; SMN2RAB9A | |
| SCHEMBL7960446 | 0.86 | RAB9A (0.57) | MAPTTP53SMN1; SMN2RAB9ALMNA | |
| SCHEMBL7964551 | 0.85 | HRH3 (0.42) | USP2CASP1HSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL7420722 | 0.85 | MAPT (0.41) | USP2CASP1HSD17B10MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639760-A | USEFUL AS MUSCLE RELAXANTS, SEDATIVES, ANXIOLYTICS, ANTICONVULSANTS, AND ANTIDOTES FOR DRUG OVERDOSE | MARYANOFF BRUCE E (US) | 1997-06-17 | — | — | US | claimed |
| US-6218384-B1 | FOR THERAPY OF ANXIETY, MUSCLE SPASMS, SLEEPLESSNESS, CONVULSIONS AND BENZODIAZEPINE OVERDOSES | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2001-04-17 | — | — | US | disclosed |
| US-5639760-A | USEFUL AS MUSCLE RELAXANTS, SEDATIVES, ANXIOLYTICS, ANTICONVULSANTS, AND ANTIDOTES FOR DRUG OVERDOSE | MARYANOFF BRUCE E (US) | 1997-06-17 | — | — | US | disclosed |