Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.47 |
| ▸ | TUBB | P07437 | 3/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7420636 | 0.89 | SMN1; SMN2 (0.47) | RAB9ASMN1; SMN2MAPK1ALDH1A1MEN1 | |
| SCHEMBL7959855 | 0.88 | LMNA (0.44) | RAB9ASMN1; SMN2MAPK1MAPTKMT2A | |
| SCHEMBL7418952 | 0.88 | RAB9A (0.44) | RAB9ASMN1; SMN2KMT2ANPC1LMNA | |
| SCHEMBL7964418 | 0.88 | RAB9A (0.44) | RAB9ASMN1; SMN2MAPK1MAPTMEN1 | |
| SCHEMBL7949930 | 0.87 | MAPT (0.54) | RAB9ASMN1; SMN2MAPK1MAPTTUBB4A | |
| SCHEMBL7961855 | 0.86 | SMN1; SMN2 (0.55) | RAB9ASMN1; SMN2MAPK1MAPTALDH1A1 | |
| SCHEMBL7411535 | 0.86 | SMN1; SMN2 (0.55) | RAB9ASMN1; SMN2MAPK1MAPTALDH1A1 | |
| SCHEMBL7416321 | 0.86 | MAPT (0.47) | RAB9ASMN1; SMN2MAPK1MAPTTUBB4A | |
| SCHEMBL7964564 | 0.86 | USP2 (0.51) | RAB9ASMN1; SMN2MAPK1MAPTALDH1A1 | |
| SCHEMBL7958240 | 0.85 | IKBKE (0.41) | RAB9ASMN1; SMN2MAPTKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639760-A | USEFUL AS MUSCLE RELAXANTS, SEDATIVES, ANXIOLYTICS, ANTICONVULSANTS, AND ANTIDOTES FOR DRUG OVERDOSE | MARYANOFF BRUCE E (US) | 1997-06-17 | — | — | US | claimed |
| US-6218384-B1 | FOR THERAPY OF ANXIETY, MUSCLE SPASMS, SLEEPLESSNESS, CONVULSIONS AND BENZODIAZEPINE OVERDOSES | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2001-04-17 | — | — | US | disclosed |
| US-5639760-A | USEFUL AS MUSCLE RELAXANTS, SEDATIVES, ANXIOLYTICS, ANTICONVULSANTS, AND ANTIDOTES FOR DRUG OVERDOSE | MARYANOFF BRUCE E (US) | 1997-06-17 | — | — | US | disclosed |