Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.35 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.35 |
| ▸ | KLK7 | P49862 | 2/20 | 0.34 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7958649 | 0.74 | GHSR (0.37) | — | |
| SCHEMBL5227995 | 0.69 | HTR2C (0.37) | PLA2G10PLA2G5LMNASMN1; SMN2DDB1 | |
| SCHEMBL5226865 | 0.69 | LMNA (0.36) | LMNASMN1; SMN2 | |
| SCHEMBL4321471 | 0.69 | STS (0.39) | PDE4APDE4BPDE4CPDE4DSTS | |
| SCHEMBL5228056 | 0.67 | GPR119 (0.46) | PDE4APDE4BPDE4CPDE4DSTS | |
| SCHEMBL5229014 | 0.67 | STS (0.48) | PDE4APDE4BPDE4CPDE4DSTS | |
| SCHEMBL2303838 | 0.64 | KMT2A (0.43) | PDE4APDE4BPDE4CPDE4DSTS | |
| SCHEMBL14714439 | 0.63 | SLC6A2 (0.38) | AKT1SMN1; SMN2KMT2A | |
| SCHEMBL873617 | 0.63 | NR1H2 (0.51) | STSGPR119JAK2JAK1KLK7 | |
| SCHEMBL2083157 | 0.63 | NR1H2 (0.51) | STSGPR119JAK2JAK1KLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6306875-B1 | ADMINISTERING GROWTH HORMONES DIPEPTIDE COMPOUNDS WHICH ARE GROWTH HORMONE SECRETAGOGUES AND ARE USEFUL FOR THE TREATMENT AND PREVENTION OF OSTEOPOROSIS. | PFIZER INC. | 2001-10-23 | — | — | US | disclosed |