Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 2/20 | 0.46 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.46 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.40 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.40 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19748200 | 0.85 | HMGB1 (0.46) | NR1H4RARBHMGB1CXCL12KLKB1 | |
| SCHEMBL107902 | 0.84 | HMGB1 (0.58) | NR1H4RARBRXRAHMGB1CXCL12 | |
| SCHEMBL2343149 | 0.82 | ALDH1A1 (0.55) | NR1H4RARBRXRAHMGB1CXCL12 | |
| SCHEMBL1627397 | 0.82 | NR1H4 (0.51) | NR1H4RARBRXRAHMGB1CXCL12 | |
| SCHEMBL7845374 | 0.82 | KLKB1 (0.48) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL10083231 | 0.81 | NR1H4 (0.50) | NR1H4RARBRXRAHMGB1CXCL12 | |
| SCHEMBL7025446 | 0.81 | NR1H4 (0.50) | NR1H4RARBRXRAHMGB1CXCL12 | |
| SCHEMBL33493 | 0.81 | NR1H4 (0.50) | NR1H4RARBRXRAHMGB1CXCL12 | |
| SCHEMBL1146167 | 0.81 | NR1H4 (0.50) | NR1H4RARBRXRAHMGB1CXCL12 | |
| SCHEMBL1712181 | 0.81 | NR1H4 (0.50) | NR1H4RARBRXRAHMGB1CXCL12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6280900-B1 | RADIATION SENSITIVE COMPOSITION WITH ALKALINE DEVELOPER SOLUBLE IN POLYMER COATED ON SUBSTRATE | JSR CORPORATION (JP) | 2001-08-28 | — | — | US | disclosed |