Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 3/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | PYGL | P06737 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7950442 | 0.92 | HSD11B1 (0.35) | ACLYPLAUGAAHSD11B1KMT2A | |
| SCHEMBL6622645 | 0.88 | GPR17 (0.36) | GAAKMT2AGPR17ALDH1A1 | |
| SCHEMBL15754940 | 0.79 | CES2 (0.39) | GAAKMT2AALDH1A1CNR1SMN1; SMN2 | |
| SCHEMBL6029786 | 0.78 | TUBB1 (0.39) | KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8525341 | 0.78 | TDP1 (0.40) | ACLYGAAGPR17KDM4EALDH1A1 | |
| SCHEMBL6622843 | 0.77 | KMT2A (0.49) | GAAKMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL28782397 | 0.76 | CYP4F2 (0.41) | GAASCN5ASCN9AKMT2AKDM4E | |
| SCHEMBL6452278 | 0.73 | CES2 (0.40) | ACLYGPR17 | |
| SCHEMBL6881746 | 0.70 | KMT2A (0.44) | KMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5533461 | 0.70 | KMT2A (0.61) | ACLYPLAUKMT2AKDM4EPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242451-B1 | Fungicidal trihalophenyl-triazolopyrimidines | BASF AKTIENGESELLSCHAFT | 2001-06-05 | — | — | US | disclosed |