Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL348786 | 0.90 | CA1 (0.41) | TDP1TSHRACLYCA1CA2 | |
| SCHEMBL7950442 | 0.85 | HSD11B1 (0.35) | ACLYKDM4EL3MBTL1ALDH1A1GAA | |
| SCHEMBL14311187 | 0.81 | CA1 (0.35) | TDP1ACLYCA1CA2CA9 | |
| SCHEMBL14305007 | 0.81 | RAPGEF4 (0.41) | TDP1TSHRKDM4ELMNAALDH1A1 | |
| SCHEMBL14554131 | 0.80 | KDM4E (0.47) | TDP1TSHRKDM4ELMNAL3MBTL1 | |
| SCHEMBL4642241 | 0.80 | CA1 (0.39) | TDP1TSHRCA1CA2CA9 | |
| SCHEMBL4642299 | 0.80 | ALDH1A1 (0.41) | TDP1TSHRCA1CA2CA9 | |
| Hydrogen Peroxide SCHEMBL29022846 | 0.79 | CA1 (0.45) | TDP1TSHRCA1CA2CA9 | |
| SCHEMBL4641646 | 0.78 | CA1 (0.38) | TDP1TSHRACLYCA1CA2 | |
| SCHEMBL7965448 | 0.78 | ACLY (0.34) | ACLYKDM4EALDH1A1GAAGPR17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227075-B | Novel process for producing N, N' -bis [2- (1H-imidazol-4-yl) ethyl ] malonamide | 瓦伦塔有限责任公司 | 2025-01-17 | — | — | CN | disclosed |
| CN-113227075-A | Novel process for the production of N, N' -bis [2- (1H-imidazol-4-yl) ethyl ] malonamide | 制药有限责任公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-104349777-B | Compounds for the treatment of spinal muscular atrophy | PTC医疗公司 | 2018-05-01 | — | — | CN | disclosed |
| CN-105050598-B | Novel compounds as ERK inhibitors | 默沙东公司 | 2018-04-27 | — | — | CN | disclosed |
| CN-105555767-B | Substituted oxo pyridine derivative and its purposes as factor XI, plasma thromboplastin antecedent A/ blood plasma | 拜耳制药股份公司 | 2018-03-23 | — | — | CN | disclosed |
| CN-103319408-B | For the compound of prevention and therapy cardiovascular disorder | RESVERLOGIX CORP. (CA) (CA) | 2016-04-13 | — | — | CN | disclosed |
| CN-105050598-A | Novel compounds as ERK inhibitors | MERCK SHARP & DOHME | 2015-11-11 | — | — | CN | disclosed |
| CN-104349777-A | Compounds for the treatment of spinal muscular atrophy | PTC THERAPEUTICS INC | 2015-02-11 | — | — | CN | disclosed |
| US-5985883-A | FUNGICIDAL ACTIVITY AGAINST RICE BLAST DISEASE | AMERICAN CYANAMID COMPANY (US) | 1999-11-16 | — | — | US | disclosed |
| EP-0279298-B1 | TRICYCLIC TRIAZOLOPYRIMIDINE DERIVATIVES | DAIICHI SEIYAKU CO., LTD. (JP) | 1992-01-15 | — | — | EP | disclosed |
| US-4898943-A | Tricyclic triazolopyrimidine derivatives | DAIICHI SEIYAKU CO., LTD. (JP) | 1990-02-06 | — | — | US | disclosed |
| EP-0159707-B1 | TRIAZOLOPYRIMIDINE DERIVATIVES | DAIICHI SEIYAKU CO., LTD. (JP) | 1990-01-24 | — | — | EP | disclosed |
| EP-0279298-A1 | Tricyclic triazolopyrimidine derivatives | DAIICHI SEIYAKU CO., LTD. (JP) | 1988-08-24 | — | — | EP | disclosed |
| US-4652646-A | ANTIALLERGENS | DAIICHI SEIYAKU CO., LTD. (JP) | 1987-03-24 | — | — | US | disclosed |
| EP-0159707-A2 | Triazolopyrimidine derivatives | DAIICHI SEIYAKU CO., LTD. (JP) | 1985-10-30 | — | — | EP | disclosed |