Pyruvate

Pyruvate

SCHEMBL7965464

CC(=O)C(=O)[O-].CC[N+](CC)(CC)Cc1ccccc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.47
CYP2D6 P10635 2/20 0.47
TSHR P16473 2/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
TAS2R10 Q9NYW0 1/20 0.47
CYP1A2 P05177 1/20 0.47
ALPL P05186 1/20 0.42
POLB P06746 1/20 0.42
ALPG P10696 1/20 0.42
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
ALDH1A1 P00352 3/20 0.40
KDM4E B2RXH2 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CHRNA7 P36544 2/20 0.39
CHRNB4 P30926 1/20 0.39
CHRNA3 P32297 1/20 0.39
CHRM2 P08172 2/20 0.38
CHRM1 P11229 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxalic Acid SCHEMBL1050278 0.93 LMNA (0.49) LMNACYP2D6TSHRMEN1KMT2A
Acetic Acid SCHEMBL306020 0.93 LMNA (0.49) LMNACYP2D6TSHRMEN1KMT2A
Bicarbonate SCHEMBL7442433 0.91 MEN1 (0.48) LMNACYP2D6TSHRMEN1KMT2A
Oxalic Acid SCHEMBL1050280 0.91 LMNA (0.48) LMNACYP2D6TSHRMEN1KMT2A
Bicarbonate SCHEMBL28141095 0.91 LMNA (0.48) LMNACYP2D6TSHRMEN1KMT2A
Bicarbonate SCHEMBL315102 0.91 LMNA (0.50) LMNACYP2D6TSHRMEN1KMT2A
Bicarbonate SCHEMBL315104 0.91 LMNA (0.50) LMNACYP2D6TSHRMEN1KMT2A
Acetic Acid SCHEMBL27557381 0.89 LMNA (0.47) LMNACYP2D6TSHRMEN1KMT2A
Oxalic Acid SCHEMBL27769827 0.89 MEN1 (0.47) LMNACYP2D6TSHRMEN1KMT2A
Acetic Acid SCHEMBL6944290 0.89 CYP1A2 (0.47) LMNACYP2D6TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6280900-B1 RADIATION SENSITIVE COMPOSITION WITH ALKALINE DEVELOPER SOLUBLE IN POLYMER COATED ON SUBSTRATE JSR CORPORATION (JP) 2001-08-28 US disclosed