Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9772435 | 1.00 | SIGMAR1 (0.49) | SIGMAR1OPRK1OPRM1OPRD1KMT2A | |
| SCHEMBL9772412 | 0.90 | KMT2A (0.58) | SIGMAR1OPRK1OPRM1OPRD1KMT2A | |
| Hydrochloric Acid SCHEMBL9772305 | 0.89 | KMT2A (0.57) | SIGMAR1OPRK1OPRM1OPRD1KMT2A | |
| SCHEMBL6488818 | 0.88 | SIGMAR1 (0.46) | SIGMAR1OPRK1OPRM1OPRD1KMT2A | |
| SCHEMBL6488821 | 0.88 | SIGMAR1 (0.46) | SIGMAR1OPRK1OPRM1OPRD1KMT2A | |
| SCHEMBL6350169 | 0.88 | SIGMAR1 (0.65) | SIGMAR1OPRK1OPRM1OPRD1KMT2A | |
| SCHEMBL5629252 | 0.88 | SIGMAR1 (0.65) | SIGMAR1OPRK1OPRM1OPRD1KMT2A | |
| SCHEMBL7966344 | 0.86 | SIGMAR1 (0.64) | SIGMAR1OPRK1OPRM1OPRD1 | |
| SCHEMBL9644180 | 0.86 | SIGMAR1 (0.64) | SIGMAR1OPRK1OPRM1OPRD1 | |
| Niravoline SCHEMBL9250990 | 0.85 | SIGMAR1 (0.67) | SIGMAR1OPRK1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271395-B1 | E.G.,(.+-.)-N-(2,3-DIHYDRO-2-(1-PYRROLIDINYL)-1H-INDEN-1-Y1) -2 ,4-DINITRO-N-METHYL-BENZENE-ACETAMIDE; STRONG AFFINITY FOR OPTICAL RECEPTORS, CENTRAL ANALGESIC, DIURETIC, ANTIARRYTHMIC, HYPOTENSIVE AND ANTIISCHEMIC ACTIVITY. | HOECHST MARION ROUSSOL (FR) | 2001-08-07 | — | — | US | claimed |