Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 9/20 | 0.40 |
| ▸ | GRM3 | Q14832 | 6/20 | 0.40 |
| ▸ | GRM5 | P41594 | 4/20 | 0.40 |
| ▸ | GRM6 | O15303 | 4/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.40 |
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GRM8 | O00222 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22365674 | 0.80 | THRB (0.31) | EPHX2THRBCYP2C9 | |
| SCHEMBL20129585 | 0.77 | GRM5 (0.41) | GRM2GRM3GRM5GRM6GRM1 | |
| SCHEMBL26217911 | 0.75 | GRM2 (0.44) | GRM2GRM3GRM5GRM6GRM1 | |
| SCHEMBL7965513 | 0.75 | GRM2 (0.40) | GRM2GRM3GRM5GRM6GRM1 | |
| Acetic Acid SCHEMBL9166776 | 0.75 | THRB (0.41) | APLNREPHX2TSHRTHRBCYP2C9 | |
| Acetic Acid SCHEMBL9168733 | 0.75 | THRB (0.41) | APLNREPHX2TSHRTHRBCYP2C9 | |
| SCHEMBL26218007 | 0.75 | HSD11B1 (0.57) | GRM2GRM5GRM1EPHX2TSHR | |
| SCHEMBL12765568 | 0.73 | — | — | |
| SCHEMBL24064288 | 0.73 | CYP2C9 (0.43) | EPHX2CYP2C9 | |
| SCHEMBL5736238 | 0.72 | HSD11B1 (0.41) | GRM2GRM3GRM5GRM6GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6280900-B1 | RADIATION SENSITIVE COMPOSITION WITH ALKALINE DEVELOPER SOLUBLE IN POLYMER COATED ON SUBSTRATE | JSR CORPORATION (JP) | 2001-08-28 | — | — | US | disclosed |