Acetic Acid

Acetic Acid

SCHEMBL9168733

CC(=O)O.CC12CC3CC(CC(C3)C1)C2

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.41
CYP2C9 P11712 1/20 0.41
EPHX2 P34913 3/20 0.41
TSHR P16473 1/20 0.41
EPHX1 P07099 3/20 0.41
ALDH1A1 P00352 2/20 0.39
APLNR P35414 1/20 0.39
GAA P10253 2/20 0.38
FFAR3 O14843 1/20 0.37
LCK P06239 1/20 0.37
FYN P06241 1/20 0.37
NPC1 O15118 1/20 0.36
HSD17B10 Q99714 1/20 0.36
HSD11B1 P28845 1/20 0.36
GLA P06280 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL9166776 1.00 THRB (0.41) THRBCYP2C9EPHX2TSHREPHX1
Methacrylic Acid SCHEMBL12802644 0.88 EPHX2 (0.38) THRBCYP2C9EPHX2TSHREPHX1
SCHEMBL453075 0.83 GRIN1 (0.45) THRBCYP2C9EPHX2TSHR
SCHEMBL3361 0.83 GRIN1 (0.45) THRBCYP2C9EPHX2TSHR
Chloroacetic Acid SCHEMBL31264078 0.81 TSHR (0.43) THRBCYP2C9EPHX2TSHRALDH1A1
Acrylic Acid SCHEMBL2421359 0.81 THRB (0.45) THRBCYP2C9EPHX2TSHREPHX1
Bromoacetic Acid SCHEMBL1628769 0.81 TSHR (0.43) THRBCYP2C9EPHX2TSHREPHX1
Phosphine SCHEMBL25178082 0.80 GRIN1 (0.43) THRBCYP2C9EPHX2TSHR
Hydrochloric Acid SCHEMBL11259068 0.80 LMNA (0.47) THRBCYP2C9EPHX2TSHR
Ammonia Solution, Strong SCHEMBL6964589 0.80 GRIN1 (0.43) THRBCYP2C9EPHX2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0660935-A1 IMMUNOLOGICAL DETECTION USING TWO DETECTABLE LABELS GEC-MARCONI LIMITED (GB) 1995-07-05 EP claimed
EP-0653065-A1 SEPARATION METHOD GEC-MARCONI LIMITED (GB) 1995-05-17 EP claimed
WO-1994003807-A1 SEPARATION METHOD GEC-MARCONI LIMITED (GB) 1994-02-17 WO claimed
WO-1994003811-A1 IMMUNOLOGICAL DETECTION USING TWO DETECTABLE LABELS GEC-MARCONI LIMITED (GB) 1994-02-17 WO claimed
US-20120318969-A1 METHOD FOR THE DIFFERENTIATION OF ALTERNATIVE SOURCES OF NAPHTHENIC ACIDS UNIVERSITY OF PLYMOUTH (GB) 2012-12-20 US disclosed
CN-1114961-A Peptide inhibitors of cell adhesion TANABE SEIYAKU CO (JP) 1996-01-17 CN disclosed
EP-0660935-A1 IMMUNOLOGICAL DETECTION USING TWO DETECTABLE LABELS GEC-MARCONI LIMITED (GB) 1995-07-05 EP disclosed
EP-0653065-A1 SEPARATION METHOD GEC-MARCONI LIMITED (GB) 1995-05-17 EP disclosed
WO-1994012878-A1 SEPARATION METHOD GEC-MARCONI LIMITED (GB) 1994-06-09 WO disclosed
WO-1994003811-A1 IMMUNOLOGICAL DETECTION USING TWO DETECTABLE LABELS GEC-MARCONI LIMITED (GB) 1994-02-17 WO disclosed
WO-1994003807-A1 SEPARATION METHOD GEC-MARCONI LIMITED (GB) 1994-02-17 WO disclosed