Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 8/20 | 0.43 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3215543 | 0.88 | HTR6 (0.40) | HTR6ADCY5ALDH1A1KDM2BMEN1 | |
| SCHEMBL3207359 | 0.82 | NPC1 (0.42) | HTR6ADCY5ALDH1A1MEN1KMT2A | |
| SCHEMBL7947328 | 0.82 | MET (0.45) | HTR6ADCY5KDM2BCXCR4MAP4K4 | |
| SCHEMBL3222945 | 0.81 | HTR6 (0.43) | HTR6ADCY5ALDH1A1MEN1KMT2A | |
| SCHEMBL3218128 | 0.81 | MET (0.43) | HTR6ADCY5ALDH1A1MEN1KMT2A | |
| SCHEMBL3214560 | 0.81 | HTR6 (0.50) | HTR6ALDH1A1MEN1KMT2A | |
| SCHEMBL3216934 | 0.79 | HTR6 (0.43) | HTR6ADCY5ALDH1A1MEN1KMT2A | |
| SCHEMBL3215703 | 0.78 | HTR6 (0.54) | HTR6ALDH1A1 | |
| SCHEMBL3220703 | 0.78 | HTR6 (0.44) | HTR6KDM2B | |
| SCHEMBL3223782 | 0.78 | HTR6 (0.47) | HTR6KDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010021797-A1 | CONDENSED HETEROCYCLIC COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-02-25 | — | — | WO | disclosed |