Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7965666 | 1.00 | MAPT (0.37) | MAPTL3MBTL1CA9KCNN4CACNA1B | |
| SCHEMBL7684170 | 0.89 | MAPT (0.42) | MAPTL3MBTL1CA9KCNN4ALDH1A1 | |
| SCHEMBL7684171 | 0.89 | MAPT (0.42) | MAPTL3MBTL1CA9KCNN4ALDH1A1 | |
| SCHEMBL7979274 | 0.88 | L3MBTL1 (0.41) | MAPTL3MBTL1CA9ALDH1A1 | |
| SCHEMBL7979276 | 0.88 | L3MBTL1 (0.41) | MAPTL3MBTL1CA9ALDH1A1 | |
| SCHEMBL7684518 | 0.88 | CA9 (0.44) | MAPTL3MBTL1CA9KCNN4ALDH1A1 | |
| SCHEMBL7684522 | 0.88 | CA9 (0.44) | MAPTL3MBTL1CA9KCNN4ALDH1A1 | |
| SCHEMBL7690672 | 0.86 | L3MBTL1 (0.38) | MAPTL3MBTL1CA9ALDH1A1 | |
| SCHEMBL7690671 | 0.86 | L3MBTL1 (0.38) | MAPTL3MBTL1CA9ALDH1A1 | |
| SCHEMBL7684744 | 0.86 | MAPT (0.39) | MAPTL3MBTL1CA9KCNN4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303783-B1 | 1- (3-Heterocyclylphenyl) isothiourea, -isourea, -guanidine and -amidine herbicidal agents | AMERICAN CYANAMID CO. | 2001-10-16 | — | — | US | disclosed |
| EP-0985670-A1 | 1-(3-Heterocyclylphenyl)isothiourea, -isourea, -guanidine and -amidine compounds as herbicides | American Cyanamid Company (US) | 2000-03-15 | — | — | EP | disclosed |