Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3315435 | 0.87 | PTGER4 (0.47) | ALOX5NR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL7956484 | 0.80 | ALDH1A1 (0.44) | ALDH1A1HPGDL3MBTL1KMT2AKDM4E | |
| SCHEMBL7969056 | 0.77 | CYP1A2 (0.50) | AKR1B1ALDH1A1HPGDCYP2C19AKR1C3 | |
| SCHEMBL15641295 | 0.73 | AKR1B1 (0.51) | AKR1B1ALOX5NR4A1NR4A2NR4A3 | |
| SCHEMBL448107 | 0.73 | AKR1B1 (0.51) | AKR1B1ALOX5NR4A1NR4A2NR4A3 | |
| SCHEMBL8120419 | 0.73 | AKR1B1 (0.51) | AKR1B1ALOX5NR4A1NR4A2NR4A3 | |
| SCHEMBL31627566 | 0.72 | AKR1B1 (0.41) | AKR1B1ALDH1A1CYP2C9HPGDCYP2C19 | |
| SCHEMBL31627543 | 0.72 | CYP1A2 (0.44) | AKR1B1ALDH1A1CYP2C9HPGDCYP2C19 | |
| SCHEMBL27890998 | 0.71 | AKR1B1 (0.50) | AKR1B1ALOX5NR4A1NR4A2NR4A3 | |
| SCHEMBL18832089 | 0.71 | PTGER4 (0.45) | ALOX5NR4A1NR4A2NR4A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277964-B1 | MONOCLONAL ANTIBODY WHICH BINDS POLYCYCLIC AROMATIC COMPOUNDS SUCH AS PHENANTHRENE AND BENZO(A)PYRENE; SENSITIVE AND ACCURATE ENVIRONMENTAL AND EXHAUST GAS MONITORING | OSAKA GAS COMPANY LIMITED (JP) | 2001-08-21 | — | — | US | disclosed |