Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CDC25B | P30305 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | CDC25C | P30307 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956845 | 0.81 | ERBB2 (0.43) | ALDH1A1HPGDCDC25BCASP1CDC25A | |
| SCHEMBL7966054 | 0.80 | AKR1B1 (0.41) | ALDH1A1HPGDKMT2AKDM4EL3MBTL1 | |
| SCHEMBL20912990 | 0.77 | ALDH1A1 (0.47) | ALDH1A1HPGDCDC25BCASP1LTC4S | |
| SCHEMBL25156303 | 0.76 | KMT2A (0.52) | ALDH1A1HPGDCDC25BCASP1LTC4S | |
| SCHEMBL31360448 | 0.76 | KMT2A (0.52) | ALDH1A1HPGDCDC25BCASP1LTC4S | |
| SCHEMBL15203285 | 0.76 | KMT2A (0.52) | ALDH1A1HPGDCDC25BCASP1LTC4S | |
| SCHEMBL21034065 | 0.75 | KMT2A (0.52) | CASP1KMT2AKDM4EL3MBTL1MAPT | |
| SCHEMBL10412730 | 0.73 | ALDH1A1 (0.51) | ALDH1A1HPGDCDC25BCASP1LTC4S | |
| SCHEMBL14022793 | 0.72 | LTC4S (0.53) | LTC4SKMT2AMEN1 | |
| SCHEMBL14022684 | 0.72 | LTC4S (0.53) | LTC4SKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277964-B1 | MONOCLONAL ANTIBODY WHICH BINDS POLYCYCLIC AROMATIC COMPOUNDS SUCH AS PHENANTHRENE AND BENZO(A)PYRENE; SENSITIVE AND ACCURATE ENVIRONMENTAL AND EXHAUST GAS MONITORING | OSAKA GAS COMPANY LIMITED (JP) | 2001-08-21 | — | — | US | disclosed |