Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 9/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | HTR1D | P28221 | 2/20 | 0.36 |
| ▸ | HTR1B | P28222 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7964572 | 0.78 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL10623962 | 0.76 | NR3C2 (0.39) | HTR1ADRD2HTR2ANR3C2SLC6A4 | |
| SCHEMBL7556723 | 0.71 | MMP12 (0.46) | HTR1ADRD2HTR2ANR3C2SLC6A4 | |
| SCHEMBL4049030 | 0.69 | MMP12 (0.54) | NR3C2PARP1TP53MAPTTHRB | |
| SCHEMBL12808579 | 0.69 | MMP12 (0.41) | HTR1ADRD2HTR2ANR3C2SLC6A4 | |
| SCHEMBL10491107 | 0.68 | MAPT (0.46) | HTR1ADRD2HTR2ANR3C2PARP1 | |
| SCHEMBL13343855 | 0.67 | NR3C2 (0.51) | HTR1ADRD2HTR2ANR3C2SLC6A4 | |
| SCHEMBL7968012 | 0.66 | TP53 (0.42) | NR3C2PARP1TP53MAPTTHRB | |
| SCHEMBL9843624 | 0.65 | MAPT (0.43) | NR3C2TP53MAPTTHRBMMP12 | |
| SCHEMBL10592084 | 0.65 | NR3C2 (0.53) | HTR1ANR3C2SLC6A4HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294503-B1 | HERBICIDAL COMPOSITIONS CONTAINING HETEROCYCLES | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2001-09-25 | — | — | US | disclosed |