Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8411974 | 0.90 | HSD11B1 (0.47) | HSD11B1PKMALDH1A1LMNAMAPT | |
| SCHEMBL1283002 | 0.81 | F2 (0.48) | HSD11B1PKMALDH1A1LMNAMAPT | |
| SCHEMBL6754818 | 0.81 | HSD11B1 (0.47) | HSD11B1PKMALDH1A1LMNAMAPT | |
| SCHEMBL14816982 | 0.81 | PKM (0.49) | HSD11B1PKMALDH1A1LMNAMAPT | |
| SCHEMBL13839049 | 0.78 | PKM (0.46) | HSD11B1PKMALDH1A1LMNAMAPT | |
| SCHEMBL8691250 | 0.77 | HTR2A (0.54) | ALDH1A1MAPT | |
| SCHEMBL9420457 | 0.76 | CA1 (0.48) | HSD11B1PKMALDH1A1KMT2APOLB | |
| SCHEMBL19126866 | 0.75 | CA2 (0.59) | HSD11B1PKMALDH1A1KMT2ACA1 | |
| SCHEMBL18342911 | 0.74 | F2 (0.49) | HSD11B1PKMALDH1A1KMT2APOLB | |
| SCHEMBL1283000 | 0.73 | HSD11B1 (0.48) | HSD11B1PKMALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265590-B1 | NEW PROTECTED AMINO ACID DERIVATIVES USEFUL FOR PEPTIDE SYNTHESIS | HYUNDAI PHARM, IND. CO., LTD. (KR) | 2001-07-24 | — | — | US | claimed |
| EP-0765307-B1 | N ALPHA-2-(4-NITROPHENYLSULFONYL)ETHOXYCARBONYL-AMINO ACIDS | HYUNDAI PHARM IND CO LTD (KR) | 1999-10-20 | — | — | EP | claimed |
| EP-0934260-A1 | N ALPHA-2-(4-NITROPHENYLSULFONYL)ETHOXYCARBONYL-AMINO ACIDS | Hyundai Pharm. Ind. Co., Ltd. (KR) | 1999-08-11 | — | — | EP | claimed |
| WO-1998017638-A1 | Nα-2-(4-NITROPHENYLSULFONYL)ETHOXYCARBONYL-AMINO ACIDS | HYUNDAI PHARM. IND. CO., LTD. (KR) | 1998-04-30 | — | — | WO | claimed |
| EP-0765307-A1 | N ALPHA-2-(4-NITROPHENULSULFONYL)ETHOXYCARBONYL-AMINO ACIDS | Hyundai Pharm. Ind. Co., Ltd. (KR) | 1997-04-02 | — | — | EP | claimed |
| US-5616788-A | FOR SOLID PHASE PEPTIDE SYNTHESIS | HYUNDAI PHARM. IND. CO., LTD. (KR) | 1997-04-01 | — | — | US | claimed |
| WO-1996025394-A1 | Nα-2-(4-NITROPHENULSULFONYL)ETHOXYCARBONYL-AMINO ACIDS | HYUNDAI PHARM. IND. CO., LTD. (KR) | 1996-08-22 | — | — | WO | claimed |