SCHEMBL7966722

SCHEMBL7966722

C=CCSc1ccnc2ncnn12

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.40
NPSR1 Q6W5P4 1/20 0.40
KDM4E B2RXH2 6/20 0.38
RCE1 Q9Y256 1/20 0.38
GAA P10253 4/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
GLA P06280 2/20 0.37
HPGD P15428 1/20 0.37
ATM Q13315 1/20 0.37
HTT P42858 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
MAPT P10636 1/20 0.35
RAB9A P51151 1/20 0.35
POLB P06746 2/20 0.34
EGLN2 Q96KS0 2/20 0.33
RXFP1 Q9HBX9 1/20 0.33
KMT2A Q03164 1/20 0.33
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9601687 0.73 ALDH1A1 (0.45) ALDH1A1NPSR1KDM4ERCE1GAA
SCHEMBL7966725 0.71 L3MBTL1 (0.36) ALDH1A1GAASMN1; SMN2HPGDL3MBTL1
SCHEMBL10406955 0.64 ALDH1A1 (0.50) ALDH1A1KDM4ERCE1GAASMN1; SMN2
SCHEMBL8596179 0.63 SMN1; SMN2 (0.47) ALDH1A1NPSR1KDM4EGAASMN1; SMN2
SCHEMBL1650004 0.63 ALDH1A1 (0.49) ALDH1A1KDM4ERCE1GAASMN1; SMN2
SCHEMBL21686239 0.63 ALDH1A1 (0.49) ALDH1A1KDM4ERCE1GAASMN1; SMN2
SCHEMBL1332491 0.63 ALDH1A1 (0.49) ALDH1A1KDM4ERCE1GAASMN1; SMN2
SCHEMBL1333523 0.63 ALDH1A1 (0.49) ALDH1A1KDM4ERCE1GAASMN1; SMN2
SCHEMBL8411017 0.63 ALDH1A1 (0.49) ALDH1A1KDM4ERCE1GAASMN1; SMN2
SCHEMBL5090716 0.62 ALDH1A1 (0.47) ALDH1A1KDM4ERCE1GAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6277857-B1 EXCELLENT SELECTIVE FUNGICIDAL ACTIVITY AGAINST VARIOUS CROP PHYTOPATHOGENS AMERICAN CYANAMID COMPANY 2001-08-21 US disclosed