SCHEMBL8596179

SCHEMBL8596179

C=CCSc1nc2nccc(O)n2n1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.47
HPGD P15428 3/20 0.47
KDM1A O60341 2/20 0.45
ABCB1 P08183 1/20 0.42
GAA P10253 1/20 0.40
KDM4E B2RXH2 4/20 0.39
LMNA P02545 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.37
TP53 P04637 1/20 0.36
ALDH1A1 P00352 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
PTPN11 Q06124 1/20 0.35
POLB P06746 2/20 0.35
MAPT P10636 2/20 0.35
NPSR1 Q6W5P4 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CTDSP1 Q9GZU7 1/20 0.35
UBE2M P61081 1/20 0.34
DCUN1D1 Q96GG9 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8520132 0.76 KDM1A (0.67) SMN1; SMN2HPGDKDM1AABCB1KDM4E
SCHEMBL9814583 0.75 KDM4E (0.56) SMN1; SMN2HPGDGAAKDM4ELMNA
SCHEMBL9175935 0.75 RXFP1 (0.34) HPGDGAAKDM4EL3MBTL1TP53
SCHEMBL8194267 0.73 GAA (0.49) SMN1; SMN2HPGDGAAKDM4ELMNA
SCHEMBL1022307 0.68 POLB (0.42) SMN1; SMN2HPGDGAAKDM4ELMNA
SCHEMBL4311403 0.67 GAA (0.49) SMN1; SMN2HPGDABCB1GAAKDM4E
SCHEMBL6680308 0.67 GAA (0.49) SMN1; SMN2HPGDKDM1AGAAKDM4E
SCHEMBL5738824 0.67 GAA (0.56) SMN1; SMN2HPGDGAAKDM4ELMNA
SCHEMBL692444 0.66 L3MBTL1 (0.58) HPGDGAAKDM4EL3MBTL1TP53
SCHEMBL8118093 0.64 GAA (0.46) SMN1; SMN2HPGDKDM1AGAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0574331-B1 Tone control of photographic images EASTMAN KODAK CO (US) 1999-07-28 EP disclosed
EP-0573373-B1 Tone control of photographic silver images EASTMAN KODAK CO (US) 1999-07-14 EP disclosed
EP-0575262-B1 Radiographic elements with improved covering power EASTMAN KODAK CO (US) 1999-07-07 EP disclosed
US-5314790-A Tetrazoles or triazoles EASTMAN KODAK COMPANY (US) 1994-05-24 US disclosed
US-5292627-A Azole to modify tone EASTMAN KODAK COMPANY (US) 1994-03-08 US disclosed
US-5292631-A Radiographic elements with improved covering power EASTMAN KODAK COMPANY (US) 1994-03-08 US disclosed
EP-0575262-A2 Radiographic elements with improved covering power EASTMAN KODAK COMPANY (US) 1993-12-22 EP disclosed
EP-0574331-A2 Tone control of photographic images EASTMAN KODAK COMPANY (US) 1993-12-15 EP disclosed
EP-0573373-A2 Tone control of photographic silver images EASTMAN KODAK COMPANY (US) 1993-12-08 EP disclosed