Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ITK | Q08881 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.37 |
| ▸ | GALR1 | P47211 | 1/20 | 0.37 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6931344 | 0.81 | ALDH1A1 (0.45) | GAAMAPTKMT2AALDH1A1LMNA | |
| SCHEMBL6930001 | 0.81 | ALDH1A1 (0.45) | GAAMAPTKMT2AALDH1A1LMNA | |
| SCHEMBL6933633 | 0.78 | ALDH1A1 (0.43) | GAAMAPTKMT2AALDH1A1LMNA | |
| SCHEMBL6929228 | 0.78 | ALDH1A1 (0.47) | MAPTKMT2AALDH1A1LMNARAB9A | |
| SCHEMBL6026843 | 0.75 | ME2 (0.46) | GAAMAPTKMT2AALDH1A1LMNA | |
| SCHEMBL7956394 | 0.75 | EGFR (0.46) | MAPTKMT2ATDP1NOTUMALDH1A1 | |
| SCHEMBL6025954 | 0.73 | ALDH1A1 (0.46) | MAPTKMT2ANOTUMALDH1A1LMNA | |
| SCHEMBL6933173 | 0.73 | AHR (0.41) | GAAMAPTKMT2ANOTUMALDH1A1 | |
| SCHEMBL7591786 | 0.73 | AHR (0.41) | GAAMAPTKMT2ANOTUMALDH1A1 | |
| SCHEMBL7565537 | 0.73 | KDM4E (0.55) | GAAMAPTKMT2ATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265436-B1 | ANTIINFLAMMATORY AGENTS | OXIS THERAPEUTICS INC. | 2001-07-24 | — | — | US | disclosed |